is known as the bitter gourd or melon and a member of family Cucurbitaceae. It medicinal plant its fruit consumed food also. This grown in tropical well subtropical areas around world, mainly Asia, India, China, South America Brazil. Due to presence bioactive compounds like charantin, α-momorcharin cucurbitacins, some which possess potent biological actions, this used folk medicine all over wor...

The effects of (–)-(1 R ,2 S ,5 )-menthol and its dithiophosphoric derivatives - O,O-di-(–)-menthyldithiophosphoric acid, sodium, 8 ,9 -quinine, ( )-(–)-nicotinic pyridoxonium salts on the organism free-living soil nematode Caenorhabditis elegans were investigated. had no toxic effect nematodes. acid sodium salt caused dose-dependent death these substances C. developed with a lag-phase reached ...

Administration of an antifibrotic agent as an adjunct to antihelmintic treatment with the objective of morbidity reduction was investigated in the murine schistosomiasis mansoni model. Antifibrotic, beta-aminopropionitrile treatment has a profound effect on the cellular matrix composition of the liver granuloma of Schistosoma mansoni infected mice when given alone, resulting in increase macroph...

Medicinal plants have remained the major sources of drugs; in fact many of the Currently available drugs were derived either directly or indirectly from them. The Approach to new drugs through natural products has proved to be the single most successful strategy for the discovery of new drugs. In the past decade, research has been focused on scientific evaluation of traditional drugs of plant o...

Benzimidazole, which is a heterocyclic nucleus, plays an important role in various medicines. A number of therapeutic agents such as H1 antihistaminic agent clemizole, a potent opioid analgesic etonitazene, nonnucleoside antiviral compound enviroxime, for promotion of excretion of uric acid irtemazole, non sedating antihistaminic agent astemizole, anti ulcer drugs omeprazole and pentoprazole, a...

Traditional system of medicinal consists of large number of plants with various medicinal and pharmacological importances and hence represents a priceless tank of new bioactive molecules. Alpinia galanga (Linn.) Pierre is one amongst these, found all over the world. It is commonly known as ‘Kulanjan’, and has been recognized in different traditional system of medicines for the treatment of vari...

Medicinal plants have played an essential role in the development of human culture. Carica papaya Linn.is a monoecious, dioecious or hermaphrodite tree; it belongs to the family Caricaceae. It is widely cultivated throughout world and is used as food and traditional medicine, particularly as an antiseptic and contraceptive. Papaya contains many biologically active compounds. Fruit, leaves, late...

Plumeriaalba and Plumeria acuminate is small laticiferous tree or shrub is a native of tropical America, commonly known as White Champa Leaf and stem were evaluated for its phytoconstituents, which is used in several traditional medicines to cure various diseases. P. accuminata, P. alba, P. rubra, P. lancifolea, P. drastic and P. phagidenica are some of the species with medicinal utility. This ...

In the practice of chemical-toxicological analysis, cases poisoning people with certain antihelmintic drugs have become more frequent. Some antihelmintics are on WHO Model List Essential Medicines, World Health Organization's list essential medicines, which lists most effective, safest and affordable medicines. Despite worldwide recognition, effectiveness, availability low cost, they an importa...