The emergence of resistance to multiple antimicrobial agents in Gram-negative bacteria is a significant threat to public health, as it restricts the armamentarium of the clinician against these infections. The aim of this study was to determine the burden of extensively drug-resistant (XDR) and pandrug-resistant (PDR) Gram-negative bacteria at a tertiary-care centre. Antimicrobial susceptibilit...

The present study was conducted to gain an insight into drug resistance and virulence factors in extraintestinal pathogenic Escherichia coli. This study was carried out on 150 Escherichia coli isolated from extraintestinal infections. Antimicrobial susceptibility testing was done by modified Kirby Bauer disc diffusion method. Extended spectrum βlactamase (ESBL) production was confirmed by pheno...

background and objectives: presence of methicillin and multidrug resistance has associated coagulase negative staphylococci (cns) with high morbidity and mortality worldwide. the present study was carried out to study the susceptibility pattern of cns to various antimicrobial agents and to determine the prevalence of cns methicillin resistance in our hospital setting. materials and methods: a t...

Urinary tract infection (UTI) is the most commonly acquired bacterial infection. Antibiotic resistance of uropathogens has been known to increase worldwide and biofilm production being the prime cause. The objective of this study was to detect the production of biofilm by uropathogens isolated from UTIs and their antimicrobial susceptibility pattern. A total 570 urine samples from clinically su...

BACKGROUND Antimicrobial drug resistance is a global issue that affects health, economic, and social development. The problem has been attributed to misuse of antimicrobial agents. PURPOSE To identify the agents of bacterial infection in Ghana, determine their antibiogram, and the possibility of setting up a surveillance program. PATIENTS AND METHODS A prospective quantitative study set in ...

background extended-spectrum β-lactamase (esbl)-producing klebsiella pneumonia has become widespread in hospitals and is increasing in community settings. most of k. pneumonia that harbor these enzymes, display resistance to other unrelated antimicrobial agents and thus, often pose a therapeutic dilemma. objectives this study was conducted to determine the prevalence of esbl-producing k. pneumo...

introduction: p. aeruginosa is an important multi-drug resistant (mdr) opportunistic pathogen in hospital-acquired infections. several methods based on dna analysis have been used for investigating genetic diversity of p. aeruginosa isolates. among them, rep‑pcr typing has been introduced as a rapid, low cost method with high discriminatory power. the aims of this study were to investigate geno...

BACKGROUND Worldwide increase in antibiotic resistance has become one of the major problems. Optimal and rationale use of antibiotic is important to prevent resistance against most of the bacteria including Coagulase-negative Staphylococci (CoNS), which has now been recognized as an important pathogen for nosocomial infections. This study was carried out to determine efficacy of vancomycin and ...