The discovery of antibiotics represented a turning point in human history. However, by the late 1950s infections that were difficult to treat, involving resistant bacteria, were being reported. Nowadays, multiresistant strains have become a major concern for public and animal health. Antimicrobial resistance is a complex issue, linked to the ability of bacteria to adapt quickly to their environ...

From 1994 to 1997, the proportion of Neisseria gonorrhoeae highly resistant to ciprofloxacin (MIC >/=4 microg/mL) increased substantially among female sex workers (FSWs) in the Philippines. Among 1499 Filipina FSWs, we evaluated factors associated with gonococcal infection and with gonococcal antimicrobial resistance. By multivariate analysis, gonococcal infection was associated with sex with a...

background : medicinal use of plants dates long back in the history of the human beings and has recently gained a great deal of importance in treating different diseases. due to the importance of pseudomonas aeroginosa strains as agents responsible for common secondary infections and their resistance to antibiotics and disinfectants, the present study aimed at investigating the antimicrobial ef...

Salmonella is frequently reported as a cause of food-borne illness. The emergence of antimicrobial resistant Salmonella associated with meat products has heightened concerns regarding antimicrobial use in food animal production. Eighty Salmonella isolates recovered from fresh whole chicken carcasses purchased at retail outlets were examined for susceptibility to 18 antimicrobials. Fifteen serot...

infectious diseases are one of the most common causes of morbidity and mortality and the spread of resistant microorganisms is playing a significant role in this regard. the purpose of this study was to assess the trend in antimicrobial resistance of gram-positive bacteria at the main referral teaching hospital in tehran during a 4-year period. all patients' biological isolates such as blood, u...

The need to stem the growing problem of antimicrobial resistance has prompted multiple, sometimes conflicting, calls for changes in the use of antimicrobial agents. One source of disagreement concerns the major mechanisms by which antibiotics select resistant strains. For infections like tuberculosis, in which resistance can emerge in treated hosts through mutation, prevention of antimicrobial ...

To evaluate multidrug-resistant strains of Salmonella enterica serotype Typhimurium, including definitive type 104 (DT104) in the United States, we reviewed data from the National Antimicrobial Resistance Monitoring System (NARMS). In 1997 to 1998, 703 (25%) of 2,767 serotyped Salmonella isolates received at NARMS were S. Typhimurium; antimicrobial susceptibility testing and phage typing were c...

results ll-37 and its truncated analogs were effective in inhibiting the growth of pdrab and had a rapid killing ability. after exposure to the peptides, the development of the pdrab biofilm was inhibited. strong inhibitory and dispersion effects of ff/cap18 on the biofilm were confirmed by fluorescence microscopy and field emission scanning electron microscopy. conclusions this results show th...

salmonella enterica serotypes are one of the most important food borne pathogens and significant public health concerns around the world in humans and other animal species. a total of eighty three epidemiologically unrelated clinical isolates of salmonella enterica serovars were subjected to antimicrobial susceptibility testing. eleven isolates (13.1%) which were resistant to at least 4 groups ...

A total of 133 Salmonella isolates recovered from retail meats purchased in the United States and the People's Republic of China were assayed for antimicrobial susceptibility, the presence of integrons and antimicrobial resistance genes, and horizontal transfer of characterized antimicrobial resistance determinants via conjugation. Seventy-three (82%) of these Salmonella isolates were resistant...