Although many compounds have already approved for use in food as antimicrobials, research for finding greater number of these compounds are still interesting because most currently approved food antimicrobials have limited applications due to food compound interactions. Finding new food antimicrobials requires expensive investigations. Traditional herbal antimicrobial agents like sumac can play...

Inappropriate antimicrobial prescribing contributes to the global spread of antimicrobial resistance. The pending weekend with changed availability of general practitioners (GP) and increased patient concern may increase the intention to prescribe antimicrobials. The aim of this study is to analyse variation in antimicrobial prescribing between weekdays and weekend in Irish general practice. Al...

BACKGROUND Urinary tract infection (UTI) is the most common diagnosis made in prescribing antimicrobials in long-term care facilities (LTCF). The diagnostic criteria for UTI vary among institutions and prescribers. Our aim was to reduce the inappropriate use of antimicrobials in LTCFs. METHODS A team comprising infectious disease consultant, infection control nurse, and geriatrician visited a...

Wounds are a major cause of morbidity especially diabetic foot wounds. Topical antimicrobials are frequently used in day to day practice mainly in management of wounds by various healthcare professionals ranging from general practitioner to specialist surgeons. However lot of controversies exists regarding the usage of antimicrobials. This article provides an insight on the usage of various com...

Introduction In modern dairy cattle operations, antimicrobials are administered for both therapeutic and prophylactic purposes. Most antimicrobials are used therapeutically but some antimicrobials are used to prevent disease in healthy animals during periods of increased susceptibility. Mastitis is one of the most frequent infectious diseases in dairy cattle and accounts for most of the doses o...

Peptidoglycan (PG) is the major structural component of the bacterial cell wall. Bacteria have autolytic PG hydrolases that allow the cell to grow and divide. A well-studied group of PG hydrolase enzymes are the bacteriophage endolysins. Endolysins are PG-degrading proteins that allow the phage to escape from the bacterial cell during the phage lytic cycle. The endolysins, when purified and exp...