BACKGROUND Bilirubin has been recognized as an anti-oxidant. The purpose of this study was to examine whether bilirubin would act as an antioxidant for surgical stress in humans. MATERIALS AND METHODS Serum bilirubin and urinary bilirubin oxidative metabolites (BOM) were measured in 96 patients who underwent surgery. The antioxidant activity of bilirubin was assessed using BOM measured by enz...

Background and objectives:Scrophularia variegata M. Beib. (Scrophulariaceae) is a medicinal plant, used for various inflammatory diseases in Iranian Traditional Medicine. In the present study, we evaluated the immune modulation and antioxidant effects of the hydroalcoholic extract of S.  variegata. Methods: The splenocytes were harvested...

conclusions antioxidant activity of this essential oil could be somehow attributed to high contents of carvone, carvacrol and thymol. the volatile oil of this plant could have the potential of other biological activities, so further experimental investigations are recommended on this essential oil. results analyses of yellow colored essential oil yielded 88.22% of total oil with 67 components. ...

phenolic and flavonoid compounds are secondary metabolites of plants which possess various activities such as anti-inflammatory, analgesic, anti-diabetes and anticancer effects. it has been established that these compounds can scavenge free radicals produced in the body. because of this ability, not only the plants containing phenolic and flavonoid compounds but also, the pure compounds are use...

Abstract This work evaluates the in vitro antioxidant and antidiabetic activities of two metformin hydrochloride-based Schiff bases. Moreover, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay was used to examine cytotoxic effects HL1 HL2 on A549 lung cancer cell line. The bases that have been previously synthesized by using effective, green techniques, namely stirring m...

Abstract Objectives The study aims to develop a stable malnourished experimental mice model resembling the human population for future studies. Materials and Methodology At weaning, female BALB/c are separated into two groups: one receiving low protein diet (LPD, 10% protein) other commercially available normal pellet (ND, 18% protein). Model development stability were assessed using body mass ...

background: diarrhea, caused by enteroaggregative escherichia coli (eaec), is an important cause of illness and death. numerous virulent factors have been described in eaec. however, their prevalence was highly variable among eaecs of distinct geographic locations. studies have shown that dispersin (antiaggregation protein, aap) is one of the important and abundant virulent factors in eaec. in ...

introduction: periodontitis is a multi-factorial inflammatory disease of periodontium. a precise mechanism in which smoking affects periodontium is not accurately understood. this study was planned to survey salivary osteocalcin (oc) level among smokers with chronic periodontitis and its comparison to non-smoker patients which may help achieve a better understanding of mechanisms being involved...