Oxidative Stress is implicated as one of the primary factors that contribute to the development of neurodegenerative diseases like Alzheimer's Disease, Parkinsonism and neurological conditions like epileptic seizures, stroke, brain damage, neurotrauma etc. The increased formation and release of oxygen free radicals coupled with the rather low antioxidative potential of the central nervous syste...

The use of soil additives such as selenium can positively influence the antioxidative system plants, making them more tolerant to abiotic stresses. aim this work was evaluate concentration sodium selenite or selenate applied substrate that causes improve in plant growth and enzyme activities sunflower plants. treatments were divided in: control (absence selenium); 0.2 mg L-1 selenate; 0.4 0.8 s...

BACKGROUND The beneficial effects of omega-3 polyunsaturated fatty acids (n-3 PUFAs), especially in dyslipidemic subjects with a high risk of cardiovascular disease, are widely described in the literature. A lot of effects of n-3 PUFAs and their oxidized metabolites are triggered by regulating the expression of genes. Currently, it is uncertain if the administration of n-3 PUFAs results in diff...

The contents of total phenol and flavonoid 27 edible plants as well their antioxidative digestive enzymes inhibitory activities were evaluated. content the ranged from 1.28-46.80 mg gallic acid equivalent/g. DPPH, ABTS reducing power assay explored that Rubus idaeus Linn, Hibiscus sabdariffa Linn. Crataegus pinnatifida Bge. exhibited stronger antioxidant capacity among plants. 4 showed percenta...

There is strong evidence that multiple sclerosis (MS) is characterized not only by immune mediated inflammatory reactions but also by neurodegenerative processes. Accumulated data indicate that oxidative stress (OS) plays a major role in this process. Generated in excess, reactive oxygen species (ROS) lead to oxidative stress and are involved in demyelination and axonal damage in MS. ROS genera...

Diabetes mellitus (DM) is a group of metabolic diseases characterized by hyperglycaemia resulting from defects in insulin secretion, insulin action, or both. It is associated with increased oxidative stress. This study evaluates the levels of the antioxidant enzymes superoxide dismutase (SOD) and gluthathione peroxidase (GPx), as a measure of antioxidant status in Type 2 diabetics. A total of 1...

Diosgenin (a steroidal saponin of yam) has long been used as a raw material for the industrial production of steroid drugs, and reported to have a hypocholesterolemic effect by suppressing cholesterol absorption and increasing cholesterol secretion. Oxidative stress has been suggested as a main risk factor in the development of atherosclerosis. The aim of this study is to investigate the possib...

The present study evaluates the genotoxic potential of different soil samples collected from rice fields employing Allium cepa root chromosomal aberration assay using in situ and root dip modes of treatment. The study also involves assessment of oxidative stress by analyzing responses of certain antioxidative enzymes viz. catalase (CAT), ascorbate peroxidase (APX), glutathione reductase (GR), g...

Melatonin was discovered to be a direct free radical scavenger less than 10 years ago. Besides its ability to directly neutralize a number of free radicals and reactive oxygen and nitrogen species, it stimulates several antioxidative enzymes which increase its efficiency as an antioxidant. In terms of direct free radical scavenging, melatonin interacts with the highly toxic hydroxyl radical wit...

Tocotrienols have been shown many biologic functions such as antioxidant, anti-cancer, maintaining fertility and regulating the immune system and so on. In this study, after feeding with tocotrienol-rich fraction from palm oil (TRF) for 2 weeks, Balb/c nude mice were inoculated human colon SW620 cancer cell and then continued to feed TRF for 4 weeks. At termination of experiments, xenografts we...