background and aims: lemon balm l (lamiaceae) has been used in a variety of practical applications in medical sciences. its antiviral activity against herpes simplex virus type-1 (hsv-1) was investigated in cell culture. lemon balm hydroalcoholic extract was found to be non-toxic to vero cells up to concentration 800 ug/ml and inhibited the growth and development of hsv-1 in dose-dependent mann...

The goal of this study was to examine and predict antiviral peptides. Although antiviral peptides hold great potential in antiviral drug discovery, little is done in antiviral peptide prediction. In this study, we demonstrate that a physicochemical model using random forests outperform in distinguishing antiviral peptides. On the experimental benchmark, our physicochemical model aided with aggr...

background: cumin ( cuminum cyminum l . [family apiaceae]) seed essential oil is reported to have antiseptic activity. until now the antiviral properties of cumin seed extracts on viruses such as herpes simplex virus-1 (hsv-1) have not been studied. the objective of this study was to investigate the in vitro effects of aqueous, methanolic and hydroalcoholic extracts of cumin seed on hsv-1 growt...

Double-stranded RNA (dsRNA) is a common by-product of viral infections and a potent inducer of innate antiviral immune responses in vertebrates. In the marine shrimp Litopenaeus vannamei, innate antiviral immunity is also induced by dsRNA in a sequence-independent manner. In this study, the hypothesis that dsRNA can evoke not only innate antiviral immunity but also a sequence-specific antiviral...

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTAntiviral TherapeuticsPriscilla L. YangPriscilla YangMore by Priscilla Yanghttps://orcid.org/0000-0001-7456-2557Cite this: ACS Infect. Dis. 2021, 7, 6, 1297Publication Date (Web):June 1, 2021Publication History Received18 May 2021Published online1 June inissue 11 2021https://doi.org/10.1021/acsinfecdis.1c00271Copyright © 2021 American Chemical SocietyRI...

Antiviral agents have been hailed to hold considerable promise for the treatment and prevention of emerging viral diseases like H5N1 avian influenza and SARS. However, antiviral drugs are not completely harmless, and the conditions under which individuals are willing to participate in a large-scale antiviral drug treatment program are as yet unknown. We provide population dynamical and game the...