objective(s) the aim of this study was to search for new antiviral agents from herbal medicines. ethanol extracts of c. semipervirens, c. semipervirens var. horizontalis and c. semipervirens cv. cereiformis were used in experiments to test their influence on herpes viruses (hsv-1). materials and methods hela cells monolayers were infected with herpes viruses (hsv-1). antiviral activity of the p...

background and objectives: essential oils are complex mixtures containing compounds of several different functional- group classes. depending on the structure, we can distinguish monoterpenes, phenylpropanes, and other components. here in this study two monoterpene compounds of essential oils, i.e. β-pinene and limonene were examined for their antiviral activity against herpes simplex virus typ...

OBJECTIVE To calculate the expected prevalence of resistant HIV mutants before antiviral therapy. DESIGN HIV replication generates virus mutants. The prevalence of these mutants is determined by mutation and selection/fitness. Some mutations will confer drug resistance and it is crucial for the success of antiviral drug therapy to determine whether these resistant viruses are present before t...

Vaccines are the cornerstone of influenza control policy, but can suffer from several drawbacks. Seasonal influenza vaccines are prone to production problems and low efficacies, while pandemic vaccines are unlikely to be available in time to slow a rapidly spreading global outbreak. Antiviral therapy was found to be beneficial during the influenza A(H1N1)pdm09 pandemic even with limited use; ho...