In spite of the power of phage display technology to identify variant proteins with novel properties in large libraries, it has only been previously applied to one member of the serpin superfamily. Here we describe phage display of human alpha-1 proteinase inhibitor (API) in a T7 bacteriophage system. API M358R fused to the C-terminus of T7 capsid protein 10B was directly shown to form denatura...

API proliferation is expected to grow in the coming years. This growth further increased by recent trends digital transformation efforts undertaken organizations across spectrum. paper discusses benefits can leverage moving towards an economy and proposes a framework for execute successfully.

FunnyQT is a new model querying and transformation approach which is implemented as an API for the functional, JVM-based Lisp-dialect Clojure. It provides several sub-APIs for implementing different kinds of queries and transformations. For example, there is a model-to-model transformation API, and there is an in-place transformation API for writing programmed graph transformations. FunnyQT cur...

In this paper, we propose an application programming interface (API) for designing of a robot workspace. The interface is realized inside a SolidWorks computer aided design environment. Via API, the builder of the robot system can check if: a) the current robot mechanism can perform the desired work movements, b) the robot can avoid singularity, and c) the points of the robot trajectory are wit...

Occupational exposure limits for unstudied pharmaceutical synthetic intermediates are often established under the assumption that penultimate and near-ultimate intermediates have the same structure-activity and dose-response as the ultimate active pharmaceutical ingredient (API). This is seldom the case because moieties that render biological activity to the API are often protected or modified ...

This document is not a candidate for any level of Internet Standard. This document specifies the Voucher Trading System Application Programming Interface (VTS-API), which assumes that the VTS plug-in is trusted by its user. The application making calls to VTS-API ought to authenticate the VTS plug-in and securely bind the plug-in with the VTS provider information specified in the Voucher Compon...

Learning and remembering how to use APIs is hard. While codecompletion tools list all the API methods available on a given object, reading through a long list of API method names and their associated documentation is tedious, and users can be easily overloaded with too many suggestions. While several researchers proposed techniques for recommending APIs, their accuracy is low. We present a nove...

Context: Refactoring is recognized as an effective practice to maintain evolving software systems. For software libraries, we study how library developers refactor their Application Programming Interfaces (APIs), especially when it impacts client users by breaking an API of the library. Objective: Our work aims to understand how clients that use a library API are affected by refactoring activit...