p62, also called sequestosome 1 (SQSTM1), is a multifunctional signaling molecule that affects cell proliferation. Recently, we found accumulation of p62 in apocrine carcinoma of the breast, however, the biological role of p62 expression in apocrine carcinoma still remains unclear. To investigate whether p62 might contribute to tumor cell proliferation in apocrine carcinomas, we used the MDA-MB...

© 2012 The Authors. doi: 10.2340/00015555-1182 Journal Compilation © 2012 Acta Dermato-Venereologica. ISSN 0001-5555 Hidradenitis suppurativa (HS) occurs chiefly in areas rich in apocrine glands, such as the axillae and the genitocrural region, and was previously thought to originate from apocrine portal closure with subsequent bacterial infection of the apocrine sweat glands. However, it is no...

Apocrine-eccrine carcinomas are rare and associated with poor prognosis. Currently there is no uniform treatment guideline. Chemotherapeutic drugs that selectively target cancer-promoting pathways may complement conventional therapeutic approaches. However, studies on genetic alterations and EGFR and Her2 status of apocrine-eccrine carcinomas are few in number. In addition, hormonal studies hav...

Apocrine hidrocystomas are rare benign cystic tumors originating from the secretory portion of apocrine sweat glands. To the best of our knowledge, there is no evidence currently available reporting the presence of apocrine hidrocystomas in the oral cavity. Therefore, this case report aims to describe the clinical and histological features of an apocrine hidrocystoma affecting the oral mucosa. ...

Apocrine skin carcinoma is an aggressive cutaneous tumour. We report a case of apocrine carcinoma developing in a naevus sebaceous of scalp in a 45 years old male. Malignant transformation of Naevus sebaceous is a rare complication usually found in elderly patients. Most of these tumours are basal cell carcinoma or squamous cell carcinoma. Only few cases of apocrine carcinoma on naevus sebaceou...

Apocrine acne, otherwise known as hidradenitis suppurativa, is a chronic inflammatory scarring disease affecting the apocrine gland-bearing skin. We present a case of a 34-year-old woman with severe vulval apocrine acne who was successfully treated initially with prednisolone and then maintained on long-term isotretinoin. This case indicates that long-term treatment with isotretinoin may be mor...

splenic hamartoma is an unusual accidental finding with non-neoplastic feature that may be incidentally diagnosed because of its compression effect on surrounding organs. the predominant pathological feature leading diagnosis is circumscribed, un-encapsulated bulging nodules with focal fibrosis or cyst. the histopathological feature of splenic hamartoma is the positivity for cd8, and occasional...

BACKGROUND Seromucinous hamartoma, a type of epithelial hamartoma, is a rare benign glandular proliferation of the sinonasal tract and nasopharynx. Herein, we present 2 rare cases of seromucinous hamartoma arising in the nasal cavity medial to the middle turbinate. METHODS AND RESULTS This is a case report of 2 patients diagnosed with seromucinous hamartoma of the nasal cavity and a review of...

Multimodal Imaging of... Klin Monatsbl Augenheilkd hamartoma or the splenic hamartoma. The exact incidence of retinal astrocytic hamartoma (RAH) is not well known, but it is estimated at one case per 100000 births per year [1]. The astrocytic hamartoma is a neuroglial tissue and produces astrocytes within the optic nerve [2], and consequently it often appears within papillary region. Congenital...

Apocrine hidrocystoma is a benign cystic tumour. The head and neck region is the site of predilection; occurrence in the scalp is extremely rare. We report a rare case of giant apocrine hidrocystoma with an unusual presentation as scalp haematoma.