In native and primary cultures of endothelial cells, fluid shear stress elicits the tyrosine phosphorylation of the endothelial NO synthase (eNOS), however, the consequences of this modification on enzyme activity are unclear. We found that fluid shear stress induces the association of eNOS with the proline-rich tyrosine kinase 2 (PYK2) in endothelial cells and that the eNOS immunoprecipitated ...

We review recent developments in the field of microrheometry and describe a new flexure-based microrheometer (FMR) that can make measurements of the steady shear viscosity of transparent or optically-opaque complex fluids using 1-10 μl samples. We document the complex microrheology that may arise in a typical consumer product such as a skin crème, when the microstructure of the multiphase mater...

Stability of coarse particles against gravity is an important issue in dense suspensions (fresh concrete, foodstuff, etc.). On the one hand, it is known that they are stable at rest when the interstitial paste has a high enough yield stress; on the other hand, it is not yet possible to predict if a given material will remain homogeneous during a flow. Using MRI techniques, we study the time evo...

A statistically stationary and nearly homogeneous turbulent shear flow is established by an additional volume forcing in combination with stress-free boundary conditions in the shear direction. Both turbulent energy and enstrophy are stationary to a much better approximation than in previous simulations that use remeshing. The temporal fluctuations decrease with increasing Reynolds number. Ener...

We measured the coefficients of viscosity, shear rates and shear stresses of chicken small intestinal and caecal contents, including solid particles, using a tube-flow viscometer. The coefficients of viscosity of chicken small intestinal and caecal contents were correlated negatively with their shear rates, a characteristic typical of non-Newtonian fluids. The coefficient of viscosity of the sm...

This study makes use of the Tsallis entropy to predict the shear stress distribution. Given a definition of the Tsallis entropy, it is maximized by using the probability density function, which then is used to attain a novel shear stress equation. This is then employed for calculating the shear stress distribution in rectangular channels in different aspect ratios and finally, for viability, th...

Background: The study of rheological properties of blood has special interest since it is a circulating fluid exposed to shear rates during its life time. This work aims to investigate the influence of whole body gamma irradiation on the rheological properties of rat’s blood. The applied shear rate was from 12 to 375 s-1. Low shear viscosity (up to 100 s-1) depends mainly on the erythroc...

Magnetic sphere viscoelastometry, video microscopy, and the Kamiya double chamber method (Kamiya, N., 1940, Science [Wash. DC], 92:462-463.) have been combined in an optical and rheological investigation of the living endoplasm of Physarum polycephalum. The rheological properties examined were yield stress, viscosity (as a function of shear), and elasticity. These parameters were evaluated in d...

This review discusses the regulation of neutrophils by fluid shear stress in the context of factors that may govern cell mechanosensitivity and its influence on cell functions. There is substantial evidence that mechanoreceptors located on the peripheral membrane contribute to the ability of shear stress to regulate cell activity. In the case of neutrophils, the formyl peptide receptor (FPR) an...

This work numerically studies the flow pattern of a magnetic fluid filled within an annulus whose inner cylinder is moving at a constant rotational speed, while the outer cylinder is stationary but under the influence of a nonuniform external magnetic field. The magnetic field consists of four basic configurations, that is, completely circular, semicircular, quarter circular, and alternately qu...