The eleven-nineteen lysine-rich leukemia (ELL) gene undergoes translocation and fuses in-frame to the multiple lineage leukemia gene in a substantial proportion of patients suffering from acute forms of leukemia. Studies show that ELL indirectly modulates transcription by serving as a regulator for transcriptional elongation as well as for p53, U19/Eaf2, and steroid receptor activities. Our in ...

The (11;19)(q23;p13.1) translocation in acute leukemia leads to the generation of a chimeric protein that fuses MLL to the transcriptional elongation factor ELL. A novel protein was isolated from a yeast 2-hybrid screen with ELL that was named EAF1 for ELL-associated factor 1. Using specific antibodies, the endogenous EAF1 and ELL proteins were coimmunoprecipitated from multiple cell lines. In ...

We prove that any reductive group G over a non-Archimedean local field has a cuspidal complex representation.

‎In 1897‎, ‎Hensel introduced a normed space which does‎ ‎not have the Archimedean property‎. ‎During the last three decades‎ ‎theory of non--Archimedean spaces has gained the interest of‎ ‎physicists for their research in particular in problems coming‎ ‎from quantum physics‎, ‎p--adic strings and superstrings‎. ‎In this paper‎, ‎we prove‎ ‎the generalized Hyers--Ulam--Rassias stability for a‎ ...

Given a model of the theory real field with restricted analytic functions such that its value group has finite archimedean rank we show how one can extend logarithm to global values in polynomial ring over dimension rank. The logarithms are determined by algebraic data from model, namely section and an embedding into Hahn group. If coincides rational equivalent. We illustrate embed exponentiati...

OBJECTIVES To conduct a prospective randomized study comparing the efficiency of 5 different ligation systems (ELL; elastomeric ligature, SSL; stainless steel ligature, LL; leone slide ligature, PSL; passive self-ligation and ASL; active self-ligation) over the duration of mandibular crowding alleviation. MATERIALS AND METHODS Fifty consecutive patients (54.2% male, 45.8% female; mean age: 16...