We present the synthesis and structure-activity relationships of sulfonatocalix[4]arene hosts bearing novel substitutions. The calix[4]arenes are modified on upper rim at either one or two phenolic units, where dual modifications introduced regioselectively neighbouring opposing phenols. mono- di-functionalised with nitro formyl groups, remaining upper-rim sites in all cases occupied by sulphon...

Alkylation of arenes by primary alcohol triflate or methanesulfonate esters can be efficiently catalyzed by AuCl3 with silver triflate.

The first examples of intermolecular trapping of Nazarov cyclopentenyl cation intermediates by simple arenes to furnish alpha-arylcyclopentanones are described.

We report both an intermolecular C–H amination of arenes to access N-methylanilines and intramolecular variant for the synthesis tetrahydroquinolines. A newly developed, highly electrophilic aminating reagent was key direct unprotected from simple arenes. The reactions display a broad functional group tolerance employ catalytic amounts benign iron salt under mild reaction conditions.

Multilayer films composed of single-component and positively-charged tetraaminocalix[4]arenes are formed through hydrogen bonding.

A gold(III)-catalyzed carbon-carbon bond formation reaction between arenes and electron-deficient alkynes or alkenes is described. Electron-rich arenes can be efficiently functionalized with the alkyne or alkene substrates. This reaction can be run with neat reactants at ambient temperature. Under the "solventless" conditions, clean product was obtained from a reaction of equal molar amounts of...

A method for base-promoted arylation of arenes and heterocycles by aryl halides and aryl triflates is described. Additionally, in situ electrophilic trapping of ArLi intermediates generated in the reaction of benzyne with deprotonated arenes or heterocycles has been developed, providing rapid and easy access to a wide range of highly functionalized polyaryls. Base-promoted arylation methodology...

Ethylene, alpha-olefins, and vinyl arenes undergo platinum-catalyzed hydroarylation with substituted indoles in moderate to good yield.

The first selective coupling of a carbon nucleophile with methyl, ethyl, propyl, and butyl arenes in the absence of a directing group is described. Pd(OAc)2 double C-H activation displays remarkable selectivity for the terminal methyl sites in alkyl arenes, rather than the more commonly observed arene sp(2) C-H activation. Mechanistic studies indicate the intermediacy of an azlactone dimer, obt...

Bis-arene complexes of technetium represent a fundamental class of organometallic compounds. Due to complex synthetic routes, no detailed insights into their properties have been reported so far. Reacting [TcO4] with arenes in the exclusive presence of AlCl3 gives highly stable [ Tc(arene)2] + in good yields. These complexes have extraordinarily high stabilities, where oxidation is found to occ...