Assembly line balancing is significant for efficient and cost effective production of the products and is therefore gaining popularity in recent years. However, several uncertain events in assembly lines might causes variation in the task time and due to these variations there always remains a possibility that completion time of tasks might exceed the predefined cycle time. To hedge against thi...

microRNAs (miRNAs) cause mRNA degradation or translation suppression of their target genes. Previous studies have found direct involvement of miRNAs in cancer initiation and progression. Artificial miRNAs, designed to target single or multiple genes of interest, provide a new therapeutic strategy for cancer. This study investigates the anti-tumor effect of a novel artificial miRNA, miR P-27-5p,...

The Graz Cycle, a hydrogen oxygen fired double loop high temperature steam cycle, combining gas turbine philosophy with steam plant praxis, can be adapted for combustion of methane with oxygen. The resulting combustion products carbon dioxide and hydrogen oxide, i.e. high temperature steam, are mixed with cooling steam and expanded to lowest pressure and temperature. By condensing the steam, se...

This paper reviews some of the recent applications of artificial neural networks taken from various works performed by the authors over the last four years at the NASA Glenn Research Center. This paper focuses mainly on two areas. 1) Artificial neural networks application in design and optimization of aircraft/engine propulsion systems to shorten the overall design cycle. Out of that specific a...

Two experiments were conducted to test the hypothesis that cortisol interferes with the positive feedback action of estradiol that induces the luteinizing hormone (LH) surge. Ovariectomized sheep were treated sequentially with progesterone and estradiol to create artificial estrous cycles. Cortisol or vehicle (saline) was infused from 2 h before the estradiol stimulus through the time of the an...

How do circadian rhythms, alarm clocks and the light/dark cycle interact? The concept of social jetlag is informing our appreciation of the tensions and consequences of imposing an artificial temporal order upon our biology.