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The mechanism by which ATP-sensitive K 1 (K ATP ) channels open in the presence of inhibitory concentrations of ATP remains unknown. Herein, using a four-state kinetic model, we found that the nucleotide diphosphate UDP directed cardiac K ATP channels to operate within intraburst transitions. These transitions are not targeted by ATP, nor the structurally unrelated sulfonylurea glyburide, which...

38. Islam, M. S., Larsson, 0. and Berggren, P.-0. (1993) Science 262,584-585 39. Ammala, C., Larsson, O., Berggren, P.-O., Bokvist, K., Juntti-Rerggren, I,., Kindmark, H. and Rorsman, P. (1991) Nature (London) 353,849-852 40. Rerggren, P.-0.. Rorsman, P., Efendic, S.. Ostenson, C.-G., Flatt, P. R., Nilsson, T., Arkhammar, P. and Juntti-Rerggren, I,. (1992) in Nutrient regulation of insulin secr...

We examine first-order perturbative results based on jellium for the surface energy of slabs of simple metals, using various local pseudopotentials (Ashcroft, Heine-Abarenkov and evanescent core). The difference between the pseudopotential and the jellium potential is averaged along the plane parallel to the surface. We compare these perturbative results with those of the stabilized jellium mod...

In a broad sense, postcolonial literature is writing which has been “affected by the imperial process from the moment of colonization to the present day” (Ashcroft et al, 2). In India’s case, this includes novels, poetry, and drama which were written both during and after the British Raj or “Reign,” which came to a formal conclusion with Indian Independence in August 1947. Although writing from...

An obstacle in any Child Pornography (CP) investigation is the investigator’s ability to determine whether the pictures in question have been altered. Because of the court ruling in Ashcroft v. Free Speech, many agents are asked on the stand if they can prove the pictures they recovered were altered in any way. If the picture doesn’t match any known CP hashes, then it can be very difficult to p...

Andreas Hermann,1,* Ainhoa Suarez-Alcubilla,2,4 Idoia G. Gurtubay,2,3 Li-Ming Yang,3 Aitor Bergara,2,3,4 N. W. Ashcroft,5 and Roald Hoffmann1 1Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA 2Materia Kondentsatuaren Fisika Saila, Zientzia eta Teknologia Fakultatea, Euskal Herriko Unibertsitatea, UPV/EHU, 644 Postakutxatila, 48080 Bilbo, Basque Country, Sp...

Many independent nations with strong tourism economies have colonial pasts. In parts of Africa and Asia, former colonial powers have left post-colonial legacies of language, buildings, trade and diplomatic links, and government bureaucratic structures (Ashcroft, Griffiths, & Tiffin, 2007; Sharp, 2009; Zein-Alabdin, 2009). There are also strong postcolonial influences on tourism (Carrigan, 2011;...