BACKGROUND Approximately 1.2 million stillbirths occur in the intrapartum period, and a further 717,000 annual neonatal deaths are caused by intrapartum events, most of which occur in resource poor settings. We aim to test the 'double-hit' hypothesis that maternal infection in the perinatal period predisposes to neurodevelopmental sequelae from an intrapartum asphyxia insult, increasing the lik...

OBJECTIVE This study investigates the clinical value of monitoring blood levels of tumor necrosis factor-α (TNF-α), high mobility group protein Bl (HMGBl), and neuron-specific enolase (NSE), and examining an amplitude-integrated electroencephalogram (aEEG) for the diagnosis and short-term prognosis of brain damage caused by neonatal asphyxia. PATIENTS AND METHODS Sixty full-term neonates born...

BACKGROUND The ICD-10 categories of the diagnosis "perinatal asphyxia" are defined by clinical signs and a 1-minute Apgar score value. However, the modern conception is more complex and considers metabolic values related to the clinical state. A lack of consistency between the former clinical and the latter encoded diagnosis poses questions over the validity of the data. Our aim was to establis...

Background: Neonatal mortality had not changed significantly in the last decade in African countries particularly in Nigeria; however, under-five mortality had reduced significantly. Nigeria with a quarter of maternal and under-five mortality is among ten countries with the highest neonatal mortality. Previous studies had shown patterns of newborn morbidity and mortality; however, no study has ...

as fetal compensation against hypoxemia progresses, the afterload on the heart and peripheral vascular resistance increases. eventually, the right heart fails, which is transmitted to the fetal venous system, causing decreased flow during late diastole or atrial contraction and increased resistance in the ductus venosus and inferior vena cava. the ductus has forward flow during atrial contracti...

how to cite this article: chiabi a, nguefack s, mah e, nodem s, mbuagbaw l, mbonda e, tchokoteu pf, doh a. risk factors for birth asphyxia in an urban health facility in cameroon. iran j child neurol. 2013 summer; 7(3):46-54. objective the world health organization (who) estimates that 4 million children are born with asphyxia every year, of which 1 million die and an equal number survive with ...

background : homicide is killing of a human being by another human being. various methods like strangulation, cut throat, stabbing etc may be used for homicide; however combination of two mechanisms is rare. case report: hereby we present a rare case with unexpected appearance of two different mechanisms of homicide applied over same region, wherein body of a female was referred to us with hist...