Sperm DNA integrity is generally acknowledged as an essential component for human reproduction. While the negative impact of high sperm DNA fragmentation (SDF) on outcomes of natural pregnancy and assisted reproductive technology (ART) is well known, the clinical indication of SDF testing is less well defined. A recent review on clinical utility of SDF testing highlighted the different SDF assa...

Background: Infertility leads to profound human suffering, particularly on the women. Women's lack of pregnancy is both physically and socially visible, especially in high fertility societies where women are typically blamed for reproductive failures, even in cases of male infertility. Childless women are more likely to be the victims of domestic violence and may also endure various forms ...

We used placental tissue to compare the imprinted gene expression of IGF2, H19, KCNQ1OT1, and CDKN1C of singletons conceived via assisted reproduction technology (ART) with that of spontaneously conceived (SC) singletons. Of 989 singletons examined (ART n = 65; SC n = 924), neonatal weight was significantly lower (P < .001) in the ART group than in the SC group, but placental weight showed no s...

BACKGROUND Public interest in Assisted Reproductive Technology (ART) has remained high since the birth of the world's first in vitro fertilization baby, Louise Brown, in the United Kingdom. ART allows scientists to manipulate the fertilization process in order to bypass some pathological obstacles such as blocked fallopian tubes and non-functioning ovaries in the females, and blocked vas defere...

Biological technology used for purposes of human reproduction has generated a number of issues involving contract law, genetic parenthood, and public policy. One such issue arises from disagreements about the fate of frozen embryos. This issue presents special challenges to the judicial process even though historically courts have had experience in applying reason to the most emotional of issue...

Background: The practice of surrogacy is one of the most controversial procedures in infertility treatment. Despite increasing of using this technology in Iran, there are few practical data about surrogacy.There isn't any study assessing experiences of commissioning mothers about surrogate mother selection. Aim: The purpose of this study was exploring of commissioning mothers' experiences in se...

An overview is given on selected cost-drivers within an assisted reproduction technology (ART) laboratory, such as procedural costs; sperm preparations; laboratory supplies including embryo culture media and cryopreservation. Depending on the nature of an ART unit, i.e. private vs. public/tertiary, the structure of the unit will differ with regards to costs, services offered, and general patien...