abstract background: schizophrenia is a severe mental disorder and numerous genes and loci are beleived to be involved in this disease. recent studies have reported a strong genetic association between dtnbp1 (dystrobrevin-binding protein 1) gene variants and schizophrenia. methods: in this research, we used a case-control study to establish the possible association between the p1635 (rs3213207...

conclusions rs9364559 in the lpa gene may contribute to the risk of cad in the han chinese population; haplotypes which contain rs9346816-g were all associated with an increased risk of cad in this study. background mutations in the solute carrier family 22 member 3 (slc22a3), lipoprotein (a)-like 2 (lpal2), and the lipoprotein (a) (lpa) gene cluster, which encodes apolipoprotein (a) [apo (a)] ...

conclusions the obtained results confirm some previous studies regardinga gender specific association of maoa gene with the bipolar disorder. results significant associations were observed regarding maoa-ca (p = 0.016) and maoa-vntr (p = 0.004) polymorphisms in the bipolar females. there was no association between maoa-rflp and bipolar disorder. patients and methods this study is a case-control...

finding frequent patterns plays a key role in exploring association patterns, correlation, and many other interesting relationships that are applicable in tdb. several association rule mining algorithms such as apriori, fp-growth, and eclat have been proposed in the literature. fp-growth algorithm construct a tree structure from transaction database and recursively traverse this tree to extract...

background: the sporadic cases of radiation-activated multiple sclerosis (ms) has been previously described, with a few studies focused on the relationship between radiation and the risk of ms. the aim of our study was to evaluate the association between history of x-ray radiation and ms.   methods : this case-control study was conducted on 150 individuals including 65 ms patients and 85 age- a...

Introduction: Acne is a common problem in adolescent and youngage groups, for which several risk factors have been suggested.One of the risk factors is smoking. In studies on the relationshipbetween smoking and acne, conflicting results have been obtained.Method: This study was conducted on 133 male patients whowere visited at the dermatology clinic of Imam Reza hospital dueto acne as the case ...

background: coronary artery disease (cad) is a multifactorial and heterogenic disease. recently, genome-wide association studies have reported that rs1333040 (c/t) and rs1004638 (a/t) single nucleotide polymorphisms (snps) in the 9p21 locus have very strong association with cad. this study aimed to examine these associations in southwest of iran. methods: blood samples were collected from 200 c...

alzheimer's disease (ad) is a genetically heterogeneous neurodegenerative disease and late-onset type (load) is the most common form of dementia affecting people over 65 years old. calhm1 (p86l) encodes a transmembrane glycoprotein that controls cytosolic ca2+ concentrations and aß levels and p86l polymorphism in this gene is significantly associated with load in independent case controls in a ...

late-onset alzheimer's disease (load) is a neurodegenerative disorder and the most common form of dementia affecting people over 65 years old. alzheimer’s disease is a complex disease with multi-factorial etiology. inflammation has been approved to have an important role in the pathogenesis of alzheimer’s disease (ad). tnf-a is a main pro-inflammatory cytokine that plays an essential role in in...

performance   evaluation in regular periods is one of the ways in which organizations can   evaluate their performance as well as weak and strong points unifiedly and   precisely. these days, mathematical models are also used to evaluate the   efficiency and productivity of various units. these units are a collection of   education, research and service activities as input and output factors an...