In a clinical trial conducted at the China Medical University in Shenyang, China, designed to determine the inhibitory effect of Astragalus on gastric cancer cells, human peritoneal mesothelial cell (cells that lines the body's serous cavity and internal organs) was co-incubated with gastric cancer cells and/or Astragalus. The results of this study found that Astragalus could partly suppress th...

The artiodactyl astragalus has been modified to exhibit two trochleae, creating a double pullied structure allowing for significant dorso-plantar motion, and limited mediolateral motion. The astragalus structure is partly influenced by environmental substrates, and correspondingly, morphometric studies can yield paleohabitat information. The present study establishes terminology and describes d...

BACKGROUND Soil surrounding selenium (Se) hyperaccumulator plants was shown earlier to be enriched in Se, impairing the growth of Se-sensitive plant species. Because Se levels in neighbors of hyperaccumulators were higher and Se has been shown to protect plants from herbivory, we investigate here the potential facilitating effect of Se hyperaccumulators on Se-tolerant neighboring species in the...

Selenium (Se) occurs in various forms in soils, including inorganic selenite and selenate and organic selenomethionine. Plant uptake of the inorganic, but not the organic forms, has been studied extensively. Organic-Se uptake was therefore examined in two-grooved milkvetch (Astragalus bisulcatus (Hook.) Gray), a Se-accumulating forb, and western wheatgrass (Pascopyrum (Rydb.) Love), a non-Se ac...

Astragalus membranaceus, dried root extract, also known as Astragali radix, is used in traditional Chinese medicine as a tonic remedy. Moreover, it has been reported that Astragalus membranaceus could attenuate intestinal inflammation; however, the underlying mechanism for its anti-inflammatory activity in intestinal epithelial cells (IECs) remains unclear. In this study, we evaluated Astragalu...

BACKGROUND In traditional Chinese medicine, astragalus injection is used to treat diabetic nephropathy (DN). The current study was conducted to determine the effects of astragalus injection on DN by assessing potential modulation of the transforming growth factor beta TGFβ/Smad signaling pathway. METHODS Diabetic, male KKAy mice, aged 14 weeks were randomly divided into a model group and an a...

In this study, distribution of Calcium oxalate (CaOx) crystal types within generative organs of Astragalus hamosus L. and Astragalus glycyphyllos L. and crystal types of them were examined using light microscopy (LM). During cytoembryological studies on A. glycyphyllos, CaOx crystals have been observed in generative organs. Prismatic and druse type crystals were determined in different regions ...

The purpose of this study was to investigate the effect of astragalus polysaccharides (APSs), active constituents of astragalus, in the treatment of hepatocellular carcinoma (HCC) and their potential as a promising candidate for future anticancer drug development. Astragalus polysaccharide was administered at different doses to HCC H22-bearing mice to investigate their antitumor effects. Result...

Objective. To evaluate the effectiveness of astragalus injection (a traditional Chinese patent medicine) for patients with renal damage induced by hypertension according to the available evidence. Methods. We searched MEDLINE, China National Knowledge Infrastructure (CNKI), Chinese VIP Information, China Biology Medicine (CBM), and Chinese Medical Citation Index (CMCI), and the date of search s...

OBJECTIVE Astragalus is a traditional Chinese medicine to improve the function of the body. The purpose of this study is to investigate the effect of astragalus on improvement of anti-fatigue capacity in mice under simulated plateau environment. METHODS Male Kunming mice were randomly divided into the following groups: the control group, astragalus treatment groups in low dosage (LD) (1.0 g/k...