BACKGROUND Central arterial stiffness represents a well-established predictor of cardiovascular disease. Decreased circulating endothelial progenitor cells (EPCs), increased asymmetric dimethyl-arginine (ADMA) levels, traditional cardiovascular risk factors and insulin resistance have all been associated with increased arterial stiffness. The correlations of novel and traditional cardiovascular...

We study strain-controlled plastic deformation of crystalline solids via two-dimensional discrete dislocation dynamics simulations. To this end, we characterize the average stress-strain curves as well statistical properties strain bursts and related stress drops a function imposed rate stiffness specimen-machine system. The system exhibits strain-rate sensitivity such that larger results in hi...

Based on the research of a periodic forced system with soft impacts, the piecewise properties of the softimpacts system, such as asymmetric motion and singularity, were analyzed by using the Poincaré map and Runge-Kutta numerical simulation method. The routes from periodic motions to chaos, via Hopf bifurcation and grazing bifurcation, were investigated exactly. In the large constraint stiffnes...

in this article, vibration analysis of an euler-bernoulli beam resting on a pasternak-type foundation is studied. the governing equation is solved by using a spectral finite element model (sfem). the solution involves calculating wave and time responses of the beam. the fast fourier transform function is used for temporal discretization of the governing partial differential equation into a set ...

A-tracts are functionally important DNA sequences which induce helix bending and have peculiar structural properties. While A-tract structure has been qualitatively well characterized, their mechanical properties remain controversial. A-tracts appear structurally rigid and resist nucleosome formation, but seem flexible in DNA looping. In this work, we investigate mechanical properties of symmet...

Lattice-based mechanical metamaterials can be tailored for a wide variety of applications by modifying the underlying mesostructure. However, most existing lattice patterns take symmetry as starting point. We show that asymmetric more likely to have certain properties than symmetric patterns. To directly compare effects versus arrangements, constrained design space is defined. A generative proc...

Abstract In order to study the vibration of composite wind turbine blades, a Green’s function method for frequency calculation is proposed. Based on variational asymptotic and Hamilton principle, mechanical model blade, modelled as box beam with laminated structure, established by using circumferential asymmetric stiffness design. The Green used analyze blades from aspect ply angle, numerical e...

Abstract The safety of human-robot interaction is an essential requirement for designing collaborative robotics. Thus, this paper aims to design a novel variable stiffness actuator (VSA) that can provide safer physical VSA follows the idea modular design, mainly including module and drive module. transmits motion from in roundabout manner, making modularization possible. As key component module...

High precision skyrmion pinning by an intentionally created magnetic structure is important in manipulation. Here, we consider various types of disks. Among other findings, clarify that, terms position and potential landscape, one needs to distinguish thin-wall skyrmions from thick-wall because fundamental differences. A wall prefers areas with a weaker exchange stiffness, larger DMI constant, ...