OBJECTIVES The purpose of this study was to evaluate benzodiazepine receptor expression on leukocytes from patients with symptomatic or silent myocardial ischemia. BACKGROUND Silent myocardial ischemia is frequently observed in patients with coronary artery disease. Pain can be effectively controlled by various endogenous mechanisms. Benzodiazepines and their receptors play key roles in pain,...

There has been enormous interest in determining whether the presence or absence of symptoms of myocardial ischemia influence prognosis in patients with coronary artery disease (CAD). The concern has been predicated on the concept that the anginal pain associated with ischemia serves as a safety warning signal indicating the presence of myocardial ischemia and that the absence of a warning signa...

Aim: To evaluate the presence of myocardial ischemia in asymptomatic patients with intermediate and high cardiovascular (CV) risk without previously known coronary artery disease (CAD) and the value of ischemia on therapeutic decision and prognosis. Materials and methods: 75 asymptomatic patients (35 with intermediate and 40 patients with high CV risk-SCORE risk system), underwent SPECT myocard...

OBJECTIVES The aim of the study was to examine the inflammatory cytokines in patients with myocardial ischemia to evaluate whether silent ischemia patients exhibit any particular cytokine pattern. BACKGROUND Silent myocardial ischemia is frequently observed in patients with coronary artery disease. Various endogenous mechanisms control a patient's perceived intensity of pain. Among them, the ...

Silent myocardial ischemia is typically defined as objective evidence of myocardial ischemia in patients without subjective ischemia symptoms. Currently, coronary artery angiography is the gold standard for diagnosis of asymptomatic coronary artery disease (CAD). Computed tomography coronary angiography (CTCA) can visually demonstrate the morphology, trend and extent of coronary stenosis and is...

Myocardial ischemia can occur without overt symptoms. In fact, asymptomatic (or silent) ST-segment depression during ambulatory electrocardiogram monitoring occurs more often than symptomatic ST-segment depression in patients with coronary artery disease. Initial studies documented that silent ischemia provided independent prediction of adverse outcomes in patients with known and unknown corona...

Transradial access (TRA) offers important advantages over transfemoral approachs, including early patient ambulation, improved comfort, less vascular complications, lower health care costs, and reduced adverse cardiovascular events, mortality. Nevertheless, complications of TRA still exist, radial artery occlusion (RAO) occurred in up to 30% cases, a prospective ultrasound study. Due dual blood...