Prostatic hyperplasia can be induced in both intact and castrated dogs and in intact cynomolgus monkeys by the administration of androgenic steroids. Estrogenic steroids potentiate this effect in dogs. These changes also can be induced by androstenedione, which increases androgen and estrogen levels. Atamestane (ATA; 1-methyl-3,17-dione-androsta-1,4-diene), a potent aromatase inhibitor, inhibit...

Shear stress activated platelets undergo aggregation in the presence of large or unusually large von Willebrand factor (vWF) multimers without the addition of ristocetin or any other exogenous chemical. This phenomenon may be analogous to the platelet aggregation that leads to thrombosis in the narrowed arteries and arterioles of patients with atherosclerosis or vasospasm. A triphenyl-methyl co...

BACKGROUND Remote patient monitoring is increasingly integrated into health care delivery to expand access and increase effectiveness. Automation can add efficiency to remote monitoring, but patient acceptance of automated tools is critical for success. From 2010 to 2013, the Diabetes-Depression Care-management Adoption Trial (DCAT)-a quasi-experimental comparative effectiveness research trial ...

It has been demonstrated (1) that aurintricarboxylic acid (ATA) reverses beryllium-induced inhibition of plasma alkaline phosphatase both in vitro and in vivo. It was suggested (2) that the ability of ATA to reverse the enzymatic and toxicological properties of Be++ involves chelate formation between Be++ and the ortho carboxyl, hydroxyl groups in the ATA molecule and the concomitant formation ...

the study examined the role of information communication technologies in extension delivery of agricultural transformation agenda (ata) of nigeria.  the objectives were to: examine the agricultural extension delivery of ata; identify icts relevant in agricultural extension and application of ata; examine roles of icts in extension of ata and identify constraints to the use of icts in extension ...

The Alzheimer's disease (AD) aetiologic event is associated with brain inflammatory processes. In this study, we consider a haplotype of the IL-10 gene promoter region, - 1082A/- 819 T/- 592A (ATA haplotype), which is an additive and independent genetic risk factor for AD. Episodic memory change is the most striking cognitive alteration in AD. It remains unclear whether episodic memory networks...

Previous studies describe a depression in potassium-evoked, calcium-dependent transmitter release from guinea pig cerebrocortical synaptosomes in response to compression to 68 ATA with heliox. The study described in this paper was designed to evaluate whether a similar effect could be detected at lower pressures and to determine whether the effect had an abrupt onset with a fixed response or a ...

The ambition, which launched the health for all movement, was bold. It assumed that enlightened policy could raise the level of health in deprived populations and thus drive overall development. The declaration broadened the medical model to include social and economic factors, and acknowledged that activities in many sectors, including civil society organizations, shaped the prospects for impr...