نتایج جستجو برای: atll
تعداد نتایج: 284 فیلتر نتایج به سال:
Adult T-cell leukemia/lymphoma (ATLL) and cutaneous T-cell lymphomas (CTCLs) are known to frequently express CC chemokine receptor 4 (CCR4). Previously, we investigated the transcriptional control of CCR4 expression in ATLL and have found that an activating protein 1 (AP1) family member, FBJ murine osteosarcoma viral oncogene homolog (FOS)-related antigen 2 (FRA2), is consistently expressed at ...
T-cell leukemia virus type 1 (HTLV-1) is the first known human retrovirus which belongs to oncovirus family. The virus has limited geographical prevalence and the north of Khorasan is one of the areas with endemic virus (2.3-3%). Adult T-cell leukemia/lymphoma (ATLL) is a malignant proliferation of the activated CD4+ T lymphocytes and is only found in patients belonging to areas where retroviru...
Abstract Background: Adult T-cell leukemia/lymphoma (ATLL) is caused by human T-cell lymphotropic virus type-1 (HTLV-1). HTLV-1 oncogenes can induce malignancy through controlled gene expression of cell cycle checkpoints in the host cell. HTLV-I genes play a pivotal role in overriding cell cycle checkpoints and deregulate cellular division. In this study, we aimed to determine and comp...
Cell adhesion molecule 1 (CADM1) is a cell adhesion molecule that is expressed in brain, liver, lung, testis, and some kinds of cancer cells including adult T-cell leukemia/lymphoma (ATLL). Recent studies have indicated the involvement of CADM1 in cell-cell contact between cytotoxic T-lymphocytes and virus infected cells. We previously reported that cell-cell interaction between lymphoma cells ...
Ninety-six patients with the diagnosis of adult T-cell leukemia/lymphoma (ATLL) were identified in countries outside Japan and the Caribbean Basin. Seventy-four of these patients were initially diagnosed in the United States; 25 of 52 patients whose places of birth were known had been born in the United States. The detection of 14 patients born in the southeastern United States, all black, indi...
Follicular mucinosis is recognized as one of the histopathological reaction patterns characterized by the accumulation of mucin within follicular epithelium. It is induced by various causes including inflammatory diseases, and more than half of the cases are associated with malignant lymphoma, mainly mycosis fungoides. Herein, we describe the third documented case of adult T-cell leukemia/lymph...
T-cell lymphoma composes 25% of lymphoid malignancies in Japan. Peripheral T-cell lymphoma (PTCL) unspecified and adult T-cell leukemia/lymphoma (ATLL) are major subtypes of T-cell lymphoma. The Japan Clinical Oncology Group (JCOG) has conducted 7 clinical trials for aggressive non-Hodgkin's lymphoma (NHL) including T-cell lymphoma. JCOG trials revealed that patients with ATLL had an extremely ...
Adult T-cell Leukemia/Lymphoma (ATLL) is an aggressive T-cell malignancy with a poorly understood pathology that manifests from human T-lymphotropic virus type I (HTLV-1) infected T-cells, typically after long latency periods (430 years). Current treatment regimens for ATLL include zidovudine (AZT) and interferon alpha (IFN-α) combination therapy. The established usage of IFN-α in the treatment...
Adult T cell leukemia/lymphoma (ATLL) has been characterized as one of the most aggressive human neoplasias and its incidence is thought to be caused by both genetic and epigenetic alterations to the host cellular genes of T cells infected with human T cell leukemia virus type I (HTLV-I). A multilobulated nuclear appearance is an important diagnostic marker of ATLL, and we have now identified t...
t-cell leukemia virus type 1 (htlv-1) اولین رتروویروس شناخته شده انسانی و جزو خانواده انکوویروس ها است. ویژگی مهم این ویروس محدودیت شیوع جغرافیایی آن است و شمال خراسان یکی از مناطق آندمیک آلودگی به این ویروس می باشد (%3-2.3). atll )لوسمی/ لنفوم سلول t بالغین( یک پرولیفراسیون بدخیم لنفوسیت های cd4+ t فعال شده می باشد و فقط در بیمارانی که در مناطق آندمیک از نظر رتروویروس htlv-1 زندگی می کنند، دید...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید