schizophrenia is a severe psychiatric illness with a lifetime prevalence of ˜1% that imposes a huge toll on patients, their families and public health services worldwide. delusions, hallucinations, disorganized speech, grossly disorganized or catatonic behavior and negative symptoms constitute the core symptoms of schizophrenia. although the neurotransmitter dopamine plays a prominent role in t...

Plant species, plant community diversity and microbial interactions can significantly impact soil microbial communities, yet there are few data on the interactive effects of plant species and plant community diversity on soil bacterial communities. We hypothesized that plant species and plant community diversity affect soil bacterial communities by setting the context in which bacterial interac...

Background: IGF-1 and certain other cytokines have been shown to exert inflammatory/anti-inflammatory roles in chronic joint diseases. Objective: To assess the effect of IGF-1, IL-27 and IL-35, their interaction and their receptor expression in a rheumatoid arthritis model. Methods: Freund’s adjuvant-induced chronic joint inflammation was operated on 160 male rats. Animals were divided into his...

To counteract global food safety hazards related to raw consumption of ready-to-eat leafy vegetables, a method improve bacterial status using antagonistic bacteria was studied under field conditions. This is the first study identify potential Escherichia coli antagonists from native microbiota on green vegetables and evaluate their effect in an industrial production setting. Bacterial strains w...

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in the present study the effects of both cck receptor agonists and antagonists on antinociception induced by morphine in the tail-flick test have been evaluated. m orphine induced dose-dependent antinociception in mice. the response of morphine was potentiated by sulfated cholecystokinin-8 (cck-8s) but not by unsulfated cholecystokinin-8 (cck-8u). the cck receptor antagonists mk-329 and l-365, ...