Histone methyltransferase (HMT) enzymes that methylate the lysine of histones are involved in chromatin-mediated gene expression. Previously, we reported that a novel polymorphism of SUV39H2, the HMT that is required for the methylation of H3-K9, was associated with an increased risk of lung cancer in Koreans. The retinoblastoma protein-interacting zinc finger gene RIZ (PRDM2) is also a member ...

Mm Pdiey.,m Rcceuh andReachCmplez diattibuta PPR WoingPapt odurninethefindintsof k n pross and to ateouige the ehange eflides amg Bank aaffand aflothen intemaed in devdoFmnAlt issue& lhese papen ary the name: of th autha , flet adnly their view, and hould be ued and ited acor&ingly. The findings. inuepietatins. and conclusions are the autoieown.fl y should notbeauw WedtotheWordd Bank, its Board...

Co-immunoprecipitation experiments in cell extract from cultured cells or target tissues indicated that estrogen receptor was complexed with the retinoblastoma binding protein RIZ in a ligand-dependent manner. Mapping of interaction sites indicated that in both proteins the same regions and motifs responsible for the interaction of transcriptional co-activator and nuclear receptors were involve...

We examine the convective stability of hydrodynamic discs with full stratification in the local approximation and in the presence of thermal diffusion (or relaxation). Various branches of the relevant axisymmetric dispersion relation derived by Urpin are discussed. We find that when the vertical Richardson number is larger than or equal to the radial one (i.e. |Riz| ≥ |Rix|) and wavenumbers are...

A research was conducted at Pistachio Research Institute in Rafsanjan, Iran, to evaluate the effects of P. vera L. ‘Badami’, P. vera L. ‘Sarakhs’ and P. mutica F and M. ‘Beneh’ rootstocks on mineral content of leaves and kernels of ‘Owhadi’, ‘Kalleh-ghuchi’ and ‘Ahamd-aghaii’ pistachio scion cultivars. Twenty year old trees of these combinations were used during study over 2003 and 2004. Leaves...

RIZ (retinoblastoma protein-interacting zinc finger protein), also denoted PRDM2, is a transcriptional regulator and tumor suppressor. It was initially identified because of its ability to interact with another well-established tumor suppressor, the retinoblastoma protein (Rb). A short motif, IRCDE, in the acidic region (AR) of RIZ was reported to play an important role in the interaction with ...

an orchard experiment was conducted at gonabad pistachio production station., khorasan, iran (1998-2003). in some pistachio trees, especially in cv. owhadi, leaf marginal chlorosis was already observed. then, gradual drying of leaves extended to the leaves' centers up to midsummer. with respect to salinity problems, some researches were done. two orchards of pistachio known as no.6 and no....

The distal portion of chromosome 1p is one of the most commonly affected regions in human cancer. In this study of hereditary and sporadic colorectal cancer, a region of frequent deletion was identified at 32.2 centimorgans from 1ptel. Deletion breakpoints clustered in the vicinity of or inside the gene RIZ, which encodes a retinoblastoma protein-interacting zinc finger protein. Sequence analys...