background and purpose: invasive aspergillosis (ia) is one of the most common life-threatening fungal infections among the critically ill patients including intensive care unit (icu) patients. delayed diagnosis and therapy may lead to poor outcomes. diagnosis may be facilitated by a test for molecular biomarkers, i.e. detection of galactomannan (gm) antigen based on enzyme immunoassay, which is...

Introduction Burkitt lymphoma/leukemia (BL/BAL) is the most common lymphoma in children, and sporadic subtype dominant Chinese populations. MYC gene translocations are essential for BL/BAL (sBL/BAL), but other mutations also play important roles sBL/BAL. Material methods Clinical data of ten children with sBL/BAL were collected, next generation sequencing tumor tissues was carried out. Cases BL...

We have compiled the largest sample of multiwavelength spectral energy distributions (SEDs) of Broad Absorption Line (BAL) quasars to date, from the radio to the X-ray. We present new Spitzer MIPS (24, 70, and 160μm) observations of 38 BAL quasars in addition to data from the literature and public archives. In general, the mid-infrared properties of BAL quasars are consistent with those of non-...

BACKGROUND Fibrocytes are circulating precursors for fibroblasts. Blood fibrocytes are increased in patients with idiopathic pulmonary fibrosis (IPF). The aim of this study was to determine whether alveolar fibrocytes are detected in broncho-alveolar lavage (BAL), to identify their prognostic value, and their potential association with culture of fibroblasts from BAL. METHODS We quantified fi...

BACKGROUND The clinical utility of bronchoalveolar lavage (BAL) fluid galactomannan (GM) for the early diagnosis of invasive aspergillosis (IA) varies widely across studies mainly due to heterogeneity of the studied populations. METHODS We conducted a systematic review and meta-analysis of 16 studies involving 783 adults with hematological malignancies to derive summary estimates of the overa...

BACKGROUND/AIMS Early diagnosis and appropriate antimicrobial choice are crucial when managing pneumonia patients, and quantitative culture of bronchoalveolar lavage (BAL) fluid is considered a useful method for identifying pneumonia pathogens. We evaluated the quantitative yield of BAL fluid bacterial cultures in patients being treated with antimicrobials and attempted to identify factors pred...

Although the application of thoracic high-resolution computed tomography (HRCT) to clinical pulmonology has revolutionised the diagnostic approach to patients with suspected interstitial lung disease (ILD), additional testing is often needed to make a confident ILD diagnosis. Bronchoalveolar lavage (BAL) can play a significant role in making an accurate and confident diagnosis of specific forms...