Bazex-Dupre-Christol syndrome (BDCS) is an X linked dominant disorder of the hair follicle characterised by follicular atrophoderma, multiple basal cell carcinomas, hypotrichosis, milia, and localised hypohidrosis. Follicular atrophoderma (FA) are follicular funnel shaped depressions, "ice pick marks", seen most commonly on the dorsum of the hands. We describe the first known Scottish family wi...

Chronic itch could be a presenting sign of malignancy. Pruritus of lymphoma is the common prototype of paraneoplastic itch and can precede other clinical signs by weeks and months. Paraneoplastic pruritus has also been associated with solid tumors and is an important clinical symptom in paraneoplastic skin diseases such as erythroderma, Grovers disease, malignant acanthosis nigricans, generaliz...

1. Elewski BE. Clinical pearl: proximal white subungual onychomycosis in AIDS. J Am Acad Dermatol 1993; 29: 631 ^ 632. 2. Silver-Lizama E, Logemann H. Proximal white subungual onychomycosis in AIDS. Int J Dermatol 1996; 35: 290 ^ 291. 3. Noppakun NM, Head EE. Proximal white subungual onychomycosis in a patient with acquired immune de¢ciency syndrome. Int J Dermatol 1986; 25: 586 ^ 587. 4. Dompm...

Un syndrome paranéoplasique est une manifestation biologique ou clinique d'un cancer liée au cancer mais sans en être la conséquence directe ou de celle de ses métastases. Les syndromes paranéoplasiques cutanés en sont l'exemple le plus visible. Patient âgé de 72 ans suivi pour une hypertension artérielle et qui rapportait l'apparition puis l'extension rapide (en quelques mois) de lésions cutan...

Erythrokeratodermia represents a group of rare genetic diseases characterized through disorders of keratinization. Clinically, they are presenting themselves with erythematous and hyperkeratosic lesions that can be persistent or variable as to their aspect and localization. They were classified in erythrokeratodermia variabilis (EKV) and erythrokeratodermia symmetric progressive (EKSP). We are ...