Im Folgenden wird ein speziell auf die individuellen Anforderungen der Servicebus-Architektur zugeschnittenes Vorgehensmodell vorgestellt, dass sich an der evolutionären Software-Entwicklung orientiert. Dementsprechend wird kein allgemein bekanntes Modell, sondern – aufgrund des hohen Stellenwertes der Wiederverwendung – auf Standards basierende Methodiken und Techniken in den Mittelpunkt geste...

Neuromedin B (NMB) (Minamino et al., 1983), a ten residue (GNLWATGHFM-NH2, Figure 1) neuropeptide, belongs to the ranatensin subfamily of bombesin-like peptides (Erspamer, 1980) which exhibits a wide range of biological responses in the central nervous system and gastrointestinal tract including thermoregulation (Marki et al., 1981), stimulation of the secretion of gastrointestinal hormones (Gh...

The number of scientific papers published each year is growing exponentially and given the rate of this growth, automated information extraction is needed to efficiently extract information from this corpus. A critical first step in this process is to accurately recognize the names of entities in text. Previous efforts, such as SPECIES, have identified bacteria strain names, among other taxonom...

Relation classification is associated with many potential applications in the artificial intelligence area. Recent approaches usually leverage neural networks based on structure features such as syntactic or dependency features to solve this problem. However, high-cost structure features make such approaches inconvenient to be directly used. In addition, structure features are probably domainde...

Mammalian bombesin (Bn) receptors comprise 3 subtypes: BB1, BB2, BB3 (nomenclature recommended by the NC-IUPHAR Subcommittee on receptors, [117, 4]). BB1 and BB2 are activated endogenous ligands neuromedin B (NMB), gastrin-releasing peptide (GRP), GRP-(18-27). is a tetra-decapeptide, originally derived from amphibians structurally closely related to GRP. The three Bn receptor subtypes couple pr...

Mitochondria are not only the main energy generators of the cell, but also mediate several critical biochemical processes such as apoptosis, proliferation and redox homeostasis. As such, mitochondrial dysfunctions can lead to a wide variety of human diseases, including cancer and osteoarthritis (OA). In OA, mitochondrial-associated signaling has b...

Design and manufacturing technology of high pressure multistage pumps which are commonly utilized in oil and gas industries, used to be imported from foreign companies. Due to international sanctions against I. R. Iran, it started to be designed and launched domestically. Nowadays all production lines including design, manufacturing and testing of these pumps have been performed by Iranian expe...

OBJECTIVE T lymphocytes have a central regulatory role in the pathogenesis of asthma. The objective of this study was to characterize immunologically the activation stage of asthma and the functional profile of lymphocytes from induced sputum, with particular emphasis on gammadelta T cells. METHODS Induced sputum was collected from 10 patients with acute exacerbation of asthma, and from healt...