The case of a 5-month-old black female child with a linear sebaceous naevus syndrome and multiple congenital anomalies is presented. Ocular malformations consisted of colobomatous changes of the lid and retina, dermoid of the conjunctiva, chorioretinal changes, and peripapillary atrophy of the optic nerve. Systemic findings included midline cleft of the secondary palate with involvement by the ...

Recent experiments (Beckers, De Houwer, Pineño, & Miller, 2005;Beckers, Miller, De Houwer, & Urushihara, 2006) have shown that pretraining with unrelated cues can dramatically influence the performance of humans in a causal learning paradigm and rats in a standard Pavlovian conditioning paradigm. Such pretraining can make classic phenomena (e.g. forward and backward blocking) disappear entirely...

ADVANTAGESOVEREXISTING TECHNOLOGY Early detection of melanoma is the single most promising strategy to cut mortality rates of this disorder.1 Thus far, most skin disease is diagnosed by simple visual inspection and biopsy. Two factors directly influence clinical practice and patient management: first, the ability to identify lesions correctly that have the potential to be melanoma; and second, ...

Sir, The coexistence of more than one neoplasm in a single cutaneous specimen is relatively uncommon and has been defined as a collision or compound tumour (1, 2). Although some of these collision tumours may arise from the involvement of related cell types, most occur by chance (1). Melanocytic naevus has been reported as occurring associated with several different tumour types (1, 3). The ass...

Malignant melanoma is the most common cancer during pregnancy, but it is unknown whether melanocytic naevi in general are activated. A total of 381 melanocytic naevi in 34 Caucasian primigravidae were examined using spectrophotometric intracutaneous analysis (SIAscopy) technology in early pregnancy and prior to delivery. The Siagraphs of each naevus were then compared in order to evaluate chang...

BACKGROUND It is unclear which of the number or the density of naevi on the skin is the more appropriate measure of risk of melanoma. Furthermore, the relationship between the number of naevi and their density in an individual has not been explored. Thus, for example, it is unknown if larger people tend to have more naevi by virtue of having a larger skin area, or if the density of naevi is sim...

© 2015 The Authors. doi: 10.2340/00015555-1859 Journal Compilation © 2015 Acta Dermato-Venereologica. ISSN 0001-5555 Congenital hemidysplasia with ichthyosiform naevus and limb defects (CHILD) syndrome is an X-linked dominant disorder with fatality for male embryos (1, 2). The disorder is caused by mutations in NSDHL (NAD[P] H steroid dehydrogenase-like protein), which is of importance in the c...