Abstract Autophagy is a conserved intracellular catabolic pathway that removes cytoplasmic components to contribute neuronal homeostasis. Accumulating evidence has increasingly shown the induction of autophagy improves health and extends longevity in several animal models. Therefore, there great interest identification effective enhancers with potential nutraceutical or pharmaceutical propertie...

Abstract In eusocial honey bees, Apis mellifera , diet, gut microbiota and nestmates can all contribute to the health of freshly emerged individual workers, but their relative importance for longevity body weight is currently unknown. Here, we show that diet most relevant, followed by presence nestmates. Freshly workers were randomly assigned eight treatments (with or without honey/pollen, prot...

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honeybee is a pollinator that has prominent role in agriculture products and nourishment for human. so, the most number of studies like genetic improvement were done on honeybee. recent advances in knowledge of molecular genetics of bee emphasize the potential for using genetic markers to select favored traits. this research was done to determine polymorphism of loci of first foraging age (aff)...

Protection against inflammation and oxidative stress is key in slowing down aging processes. The honey bee (Apis mellifera) shows flexible aging patterns linked to the social role of individual bees. One molecular factor associated with honey bee aging regulation is vitellogenin, a lipoglycophosphoprotein with anti-inflammatory and antioxidant properties. Recently, we identified three genes in ...

Food choice and eating behavior affect health and longevity. Large-scale research efforts aim to understand the molecular and social/behavioral mechanisms of energy homeostasis, body weight, and food intake. Honey bees (Apis mellifera) could provide a model for these studies since individuals vary in food-related behavior and social factors can be controlled. Here, we examine a potential role o...

A key characteristic of eusocial species is reproductive division of labour. Honey bee colonies typically have a single reproductive queen and thousands of sterile workers. Adult queens differ dramatically from workers in anatomy, physiology, behaviour and lifespan. Young female workers can activate their ovaries and initiate egg laying; these 'reproductive' workers differ from sterile workers ...

Honey bee (Apis mellifera) gene expression related to immunity for hymenoptaecin (AmHym) and defensin-1 (AmDef-1), longevity for vitellogenin (AmVit2) and stem cell proliferation for poly U binding factor 68 kDa (AmPuf68) was compared following Varroa destructor parasitism, buffer injection and injection of V. destructor compounds in its homogenate. In adults, V. destructor parasitism decreased...

Honeybee (Apis mellifera) society is characterized by a helper caste of essentially sterile female bees called workers. Workers show striking changes in lifespan that correlate with changes in colony demography. When rearing sibling sisters (brood), workers survive for 3-6 weeks. When brood rearing declines, worker lifespan is 20 weeks or longer. Insects can survive unfavorable periods on endog...