Cryptic relatedness was suggested to be an important source of confounding in population-based association studies (PBAS). The magnitude and manner of cryptic relatedness affecting the performance of PBAS of continuous traits remain to be investigated. We simulated a set of related samples through biased sampling and inbreeding, and evaluated the power and type I error rates of simple associati...

The current geological and tectonic setting of Iran is due to the ongoing convergence between the Arabian and Eurasian Plates, which resulted in the formation of the Iranian plateau, mountain building, extensive deformation and seismicity. The Iranian plateau is characterized by various domains including the continental collision and the oceanic plate seduction. Based on S receiver functions ar...

Government involvement in quality assurance is becoming the trend in many countries, including New Zealand. What values underpin the systems that evolve in each country, and who has given legitimacy to them? In the context of the prevailing ideology of early childhood, this paper unpacks quality assurance in Australia and comments on the assumptions, taken for granted premises and values which ...

The activation of cryptic 5' splice sites (5' SSs) is often related to human hereditary diseases. The DNA-based mutation screening strategies are commonly used to recognize the cryptic 5' SSs, because features of the local DNA sequence can influence the choice of cryptic 5' SSs. To improve the identification of the cryptic 5' SSs, we developed a structure-based method, named SPO (structure prof...

Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae) is a cryptic species complex, causing significant crop losses in China during the last decade. Although knowledge of cryptic species composition and dynamics within B. tabaci complex is critical for developing sustainable pest management strategies, limited information is available on this pest in the Henan province of China. A systematic surv...

Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae) is a cryptic species complex that includes some of the most significant pests of agriculture and horticulture worldwide. To understand the diversity and distribution of B. tabaci cryptic species in Yunnan, a famous biodiversity hotspot in China, a large-scale sampling was conducted from year 2010 to 2013 in 10 prefectures. Mitochondrial cytoch...

Cryptic genetic variants that do not typically influence traits can interact epistatically with each other and mutations to cause unexpected phenotypes. To improve understanding of the genetic architectures and molecular mechanisms that underlie these interactions, we comprehensively dissected the genetic bases of 17 independent instances of the same cryptic colony phenotype in a yeast cross. I...

Cytolytic T cells eliminate infected or cancer cells by recognizing peptides presented by MHC class I molecules on the cell surface. The antigenic peptides are derived primarily from newly synthesized proteins including those produced by cryptic translation mechanisms. Previous studies have shown that cryptic translation can be initiated by distinct mechanisms at non-AUG codons in addition to c...

We conduct waveform inversion to infer the three-dimensional (3-D) S-velocity structure in the lowermost 400 km of the mantle (the D′′ region) beneath the Northern Pacific region. Our dataset consists of about 20,000 transverse component broadband body-wave seismograms observed at North American stations for 131 intermediate and deep earthquakes which occurred beneath the western Pacific subduc...