AIM To report periorbital dermatitis as a late side effect of topical dorzolamide hydrochloride (Trusopt), a drug used to reduce intraocular pressure. METHODS A retrospective study of 14 patients who developed periorbital dermatitis while using topical dorzolamide hydrochloride was undertaken. Six patients underwent patch testing for sensitivity to Trusopt, dorzolamide hydrochloride, and the ...

To evaluate corneal sensitivity by using the Cochet-Bonnet® esthesiometer in normal canine eyes at different time points following instillation of three different topical non-steroidal anti-inflammatory drugs (flurbiprofen sodium 0.03%, diclofenac sodium 0.1% and ketorolac tromethamine 0.5%) and benzalkonium chloride 0.01%. Six healthy mixed breed dogs from the same litter were used in two diff...

Background and Aim: Coronavirus disease-2019 (COVID-19) impacts increasing the use of disinfectants (benzalkonium chloride), which indirectly accumulate in water. The disinfectant accumulation waters has been studied, but there no study its impact on aquatic commodities, especially fish with a high sensitivity, one is goldfish (Carassius auratus). Benzalkonium chloride can potentially affect se...

Antimicrobial chemicals are widely applied to clean and disinfect food-contacting surfaces. However, the cellular response of bacteria to various disinfectants is unclear. In this study, the physiological and genome-wide transcriptional responses of Bacillus cereus ATCC 14579 exposed to four different disinfectants (benzalkonium chloride, sodium hypochlorite, hydrogen peroxide, and peracetic ac...

Antimicrobial chemicals are widely applied in the food processing industry. In attention to extent uses of disinfectants, it is necessary to evaluate and certificate the efficacy of disinfectants and employing the minimum effective dosages. In this research the antibacterial influences of a common disinfectant solution used in food industry, benzalkonium chloride that is a quaternary ammonium c...

The aim of this study was to prepare and characterize a potential drug support system based on surfactant/zeolite composites for anti-inflammatory drugs. In order to increase the adsorbing capacity the external surface of the natural zeolite clinoptilolite was modified with benzalkonium chloride in the treatments raging from 100% to 300% of the zeolite external cation exchange capacity. Adsorpt...

During a 6-week period, 10 patients were admitted to a hospital for treatment of knee or shoulder joint infections due to Serratia species. Isolates from eight patients were identified as Serratia marcescens with identical biochemical characteristics and antibiotic susceptibility patterns. Before the onset of infections, all patients had been treated by two orthopedic surgeons who shared an off...