BACKGROUND To assess the effects of single polycyclic aromatic hydrocarbons (PAHs) on solid tumor initiation, and investigate their roles in immune response regulation. MATERIAL AND METHODS Mice (100) were randomly divided into 5 groups (n=20) to be intraperitoneally injected with 10 daily doses of DMSO (control), anthracene (50 mg/kg), benzo-(a)-pyrene (10 mg/kg), benzo-(a)-pyrene (20 mg/kg)...

Uptake of benzo(a)pyrene by living cultured cells has been visualized in real time using digital fluorescence-imaging microscopy. Benzo(a)pyrene was noncovalently associated with lipoproteins, as a physiologic mode of presentation of the carcinogen to cells. When incubated with either human fibroblasts or murine P388D1 macrophages, benzo(a)pyrene uptake occurred in the absence of endocytosis, w...

BACKGROUND A climate-controlled pot experiment was conducted to investigate the effects of planting alfalfa and applying organic fertilizer on the dissipation of benzo[a]pyrene from an aged contaminated agricultural soil. RESULTS Short-term planting of alfalfa inhibited the dissipation of benzo[a]pyrene from the soil by 8.9%, and organic fertilizer enhanced benzo[a]pyrene removal from the soi...

The study investigated the influence of maturity, biomass type, and depositional settings on distribution relative abundance polycyclic aromatic hydrocarbons (PAHs) for lacustrine sediments collected from depths up to 1000 m Prebreza ?u?ale stratigraphic units (the northwest part Toplica Basin). A recently proposed benzo[ghi]perylene/(perylene + benzo[ghi]perylene) parameter, along with commonl...

The occurrence and levels of benzo[a]pyrene in various heat-treated foods from China were evaluated by high-performance liquid chromatography-fluorescence detection. In a total of 119 samples, 105 were found to contain benzo[a]pyrene at levels of 0.03 to 19.75 μg/kg. The benzo[a]pyrene contents in 12 animal source foods were higher than the Chinese maximum permissible level in food (5 μg/kg) an...

The aim of the study was to identify and quantify concentrations potential sources Polycyclic Aromatic Hydrocarbons (PAHs) present in dust particles at fuel filling stations Tamale Metropolis. Sixteen USEPA recognised PAHs were identified after samples analysed their using PAH isomeric ratios. Sample extraction conducted an Accelerated Solvent Extractor (ASE) levels further GC-MS system. total ...

A gold(I)-catalyzed 6-endo-dig cyclization of aromatic 1,5-enyne was developed to synthesize 2-(naphthalen-2-yl)aniline. The functional group tolerance this examined systematically and a possible mechanism proposed. derivatization 2-(naphthalen-2-yl)aniline carried out facile access benzo[α]carbazole, benzo[c,h]cinnoline dibenzo[i]phenanthridine derivatives in divergent way.

The metabolism of benzo(a)pyrene in cultured human colon has been investigated. Nontumorous colonie tissue was collected at the time of either surgery or "immediate autopsy" from patients with or without colonie cancer. After 24 hr in culture the expiants were exposed to [3H]benzo(a)pyrene for another 24 hr and the binding to cellular DMA and protein was measured. Two adducts, formed between be...

The reactions of benzo[e][2,1]thiazine-4-chloro-3-carbaldehydes 1 and benzo[e][2,1]thiazine-4-chloro-3-carbonitriles 2 with a number of oxidizing and reducing agents are reported. A number of new, highly functionalized benzo[e][2,1]thiazine derivatives having potential biological activity were synthesized and described.