Effects of 6 substances of 29 specifically expressed in the pre-simbiotic phase of Tuber borchii − Tilia americana interaction and root extracts obtained in water and ethanol were tested on T. borchii mycelium. Root extracts increased hyphal branching; this is in agree with data obtained using only endo-mycorhhizal fungi. The tested substances showed various effects on morphology and features o...

Series of 3, 4-disubstituted benzaldehyde-N-(6-substituted-1,3-benzothiazol2-yl)semicarbazones (4a-t) were synthesized by condensation of the N(substituted-1,3-benzothiazol-2-yl)hydrazinecarboxamides with aromatic aldehydes and screened for their anticonvulsant activity using the maximal electroshock seizure (MES) method. The selected compounds were checked for the neurotoxicity by rotorod test...

Various N-(5-chloro-6-substituted-benzothiazol-2-yl)-N'-(substituted phenyl)-[1,3,4]thiadiazole-2,5-diamines (5a-t) were designed and synthesized starting from substituted acetophenones. Structures of all the compounds were confirmed on the basis of spectral and elemental analyses. All the newly synthesized compounds were screened for their anticonvulsant activity and were compared with the sta...

The minor groove binding asymmetric cyanine dye 4-[(3-methyl-6-(benzothiazol-2-yl)-2,3-dihydro- (benzo-1,3-thiazole)-2-methylidene)]-1-methyl-pyridin ium iodide (BEBO) is tested as sequence non- specific label in real-time PCR. The fluorescence intensity of BEBO increases upon binding to double-stranded DNA allowing emission to be measured at the end of the elongation phase in the PCR cycle. BE...

A series of new benzothiazole derivatives 6a-h have been synthesized, in five steps, from substituted phenols via the 1,3,4-oxadiazole-2-thiones 5a-h. The in vitro antitumor activity of the compounds obtained was investigated and the benzothiazol derivatives 6d and 6e showed strong effects on leukaemia cell lines CCRF-CEM (CC50=12+/-2 micromol L(-1), 8+/-1 micromol L(-1), respectively). These c...

The title compounds 6aâj, 2-[(6-methyl-1,3-benzothiazol-2-yl)amino]-N-[2-(substituted phenyl/furan-2-yl)-4-oxo-1,3-thiazolidin-3-yl]nicotinamides, were prepared from 2-chloropyridine-3-carboxylic acid (1) and 2-amino-6-methyl-benzothiazole (2) by known methods. All the compounds have been established by IR, (1)H NMR, (13)C NMR and elemental analyses. The in vitro antimicrobial screening of the ...

The title dinuclear complex, [Re2(C13H8NOS)2(CO)6], crystallizes in two polymorphs where the 2-(1,3-benzothiazol-2-yl)phenolate ligands and two carbonyl groups are trans(I) or cis-arranged (II) with respect to the [Re2O2(CO)4] core. Polymorphs I and II exhibit a crystallographically imposed centre of symmetry and a twofold rotation axis, respectively. The structures may be described as being fo...