نتایج جستجو برای: bhk rabies vaccine
تعداد نتایج: 116080 فیلتر نتایج به سال:
Background: Rabies is anacute viraldisease ofthe central nervous systemand themortality rateis veryhighand one hundredpercent.Rabies transmitted to-human through the bite of a rabid animal, especially canine and feline. Annual, 40 to 70 million deaths occur worldwide from rabies. Rabiesincubation periodwas reported of 5 days toayearand an average of 3-1months. The aim of this study was reported...
Thirty-two seronegative pups were vaccinated at 8 weeks of age with modified-live canine distemper virus (CDV), canine adenovirus type-2 (CAV-2), and canine parvovirus (CPV) vaccine and at 12 weeks with a modified-live CDV, CAV-2, CPV, and killed rabies virus vaccine. An additional 31 seronegative pups served as age-matched, nonvaccinated controls. All test dogs were strictly isolated for 3 yea...
Although effective rabies virus vaccines have been existing for decades, each year, rabies virus infections still cause around 50.000 fatalities worldwide. Most of these cases occur in developing countries, where these vaccines are not available. The reasons for this are the prohibitive high costs of cell culture or egg grown rabies virus vaccines and the lack of a functional cold chain in many...
Abstract Background: Rate of bites from animals suspected with rabies is increasing in Iran and post-exposure prophylaxis imposes a massive burden on the health system. This study is performed to assess the trend and the current status of animal bites in Tehran. Materials and methods: During the years of 1993-4 and 2008-9, data was collected from the records of persons bitten by animals sus...
OBJECTIVE To evaluate postexposure prophylaxis (PEP) in dogs experimentally infected with rabies. ANIMALS 29 Beagles. PROCEDURE Dogs were sedated and inoculated in the right masseter muscle with a salivary gland homogenate from a naturally infected rabid dog (day 0). Six hours later, 5 dogs were treated by administration of 2 murine anti-rabies glycoprotein monoclonal antibodies (mAb) and c...
Background: During the one-year period from May 2008 to May 2009, a nationwide shortage developed which rabies vaccine was not being produced by the manufacturers. In order to manage existing supply, a protocol was established wherein an authorization was required from the regional poison center before vaccine could be administered to a patient. Methods: The Georgia Poison Center internal datab...
Suspension cultures of BHK-21 cells maintained at 32 to 33 C were infected with the Flury LEP strain of rabies virus. By using a cell concentration of 2.0 x 10(6) to 2.5 x 10(6) cells per ml infected at a multiplicity of 0.05, high titers of extracellular virus were reached in 96 to 120 h, and potent inactivated vaccines were prepared from culture fluids harvested between 96 to 168 h. The addit...
Baits laden with oral rabies vaccines are important for the management of wildlife rabies in the United States. In August 2012, the Wildlife Services program of the U.S. Department of Agriculture's Animal and Plant Health Inspection Service began a field trial involving limited distribution of a new oral rabies vaccine bait in five states, including Ohio. The vaccine consisted of live recombina...
Rabies virus leader RNA was detected in infected BHK-21 cell extracts by hybridization to end-labeled genomic RNA. Similar to the leader RNA of vesicular stomatitis virus, the leader RNA of rabies virus was also found to be associated with the La protein by specific immunoprecipitation with antisera from lupus patients. The 3' end of the genomic RNA of rabies virus was sequenced, and the size a...
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