We study the relationship between two key concepts in the theory of digraphs, those of quotient digraphs and voltage digraphs. These techniques contract or expand a given digraph in order to study its characteristics, or obtain more involved structures. As an application, we relate the spectrum of a digraph Γ, called voltage digraph or base, with the spectrum of its lifted digraph Γ. We prove t...

Mader conjectured that for all ` there is an integer δ(`) such that every digraph of minimum outdegree at least δ(`) contains a subdivision of a transitive tournament of order `. In this note we observe that if the minimum outdegree of a digraph is sufficiently large compared to its order then one can even guarantee a subdivision of a large complete digraph. More precisely, let ~ G be a digraph...

Let D be a digraph, V (D) and A(D) will denote the sets of vertices and arcs of D, respectively. A (k, l)-kernel N of D is a k-independent set of vertices (if u, v ∈ N , u 6= v, then d(u, v), d(v, u) ≥ k) and l-absorbent (if u ∈ V (D) − N then there exists v ∈ N such that d(u, v) ≤ l). A k-kernel is a (k, k − 1)-kernel. Quasi-transitive, right-pretransitive and left-pretransitive digraphs are g...

In this paper we introduce the Cayley digraph structure. This can be considered as a generalization of Cayley digraph. We prove that all Cayley digraph structures are vertex transitive. Many graph theoretic properties are studied in terms of algebraic properties.

The oral delivery of protein and peptide drugs is limited by their proteolytic degradation and the poor absorption across the intestinal epithelia. In this work, we exposed a phage library of small bicyclic peptides (<1.5 kDa) to a pancreatic extract of proteases prior to affinity selection to enrich binders with higher stability in the intestinal environment. Panning with the therapeutic targe...

In a Cayley digraph on a group G, if a distinct colour is assigned to each arc-orbit under the left-regular action of G, it is not hard to show that the elements of the left-regular action of G are the only digraph automorphisms that preserve this colouring. In this paper, we show that the equivalent statement is not true in the most straightforward generalisation to G-vertex-transitive digraph...

If ∗ : G → G is an involution on the finite group G, then ∗ extends to an involution on the integral group ring Z[G]. In this paper, we consider whether bicyclic units u ∈ Z[G] exist with the property that the group 〈u, u∗〉, generated by u and u∗, is free on the two generators. If this occurs, we say that (u, u∗) is a free bicyclic pair. It turns out that the existence of u depends strongly upo...

Let ∆(G), ∆ for short, be the maximum degree of a graph G. In this paper, trees (resp., unicyclic graphs and bicyclic graphs), which attain the first and the second largest spectral radius with respect to the adjacency matrix in the class of trees (resp., unicyclic graphs and bicyclic graphs) with n vertices and the maximum degree ∆, where ∆ ≥ n+1 2 (resp., ∆ ≥ n 2 +1 and ∆ ≥ n+3 2 ) are determ...

A connected graph of order n is bicyclic if it has n+1 edges. He et al. [C.X. He, J.Y. Shao, J.L. He, On the Laplacian spectral radii of bicyclic graphs, Discrete Math. 308 (2008) 5981–5995] determined, among the n-vertex bicyclic graphs, the first four largest Laplacian spectral radii together with the corresponding graphs (six in total). It turns that all these graphs have the spectral radius...

Many biologically active peptides found in nature exhibit a bicyclic structure wherein a head-to-tail cyclic backbone is further constrained by an intramolecular linkage connecting two side chains of the peptide. Accordingly, methods to access macrocyclic peptides sharing this overall topology could be of significant value toward the discovery of new functional entities and bioactive compounds....