PURPOSE To demonstrate a progressive approach to the problems of intraoperative floppy-iris syndrome (IFIS) in cataract surgery caused by tamsulosin. SETTING Cataract Treatment Center, Sunderland Eye Infirmary, Sunderland, United Kingdom. METHODS Thirty-two eyes of 20 patients who were using tamsulosin had cataract surgery by the same surgeon using the same technique. Patients received stan...

Since intraoperative floppy iris syndrome (IFIS) was first described in 2005, its association with the systemic alpha-1 adrenergic antagonist, tamsulosin (Flomax®, Boehringer-Ingelheim Pharmaceuticals, Inc., Ridgefield, CT), has become well established [1-7]. The clinical manifestations of IFIS complicating cataract surgery are poor preoperative pupil dilation, iris billowing and prolapse, and ...

Mitral valve regurgitation (MR) is the most common valvular heart disease. Diagnosing and managing mitral often challenging requires a structured approach, integrating findings on history, physical examination imaging. A cardiac anomaly myxomatous prolapse. Excess leaflet tissue, bileaflet prolapse or billowing, chordae elongation annular dilatation are all features of Barlow’s Currently, there...

This case, involving a 74 year old man who underwent mitral valve and aortic valve replacements, provides detailed insight into the perioperative echocardiographic and haemodynamic changes occurring when a mitral valve prosthesis intermittently obstructs. It illustrates the early sequence of electromechanical dissociation which would lead to cardiac arrest should a tilting disc prosthesis be im...

Two new species of chameleons from the genera Rhampholeon and Kinyongia are described from an isolated montane forest remnant situated toward the southern end of the Albertine Rift bordering Lake Tanganyika. The closest known localities of species from these genera are 200km and 400km to the north respectively, separated by large intervening tracts of lowland savannah and Brachystegia (Miombo) ...

Intraoperative floppy iris syndrome (IFIS) was first described in 2005 (Chang & Campbell 2005; Parssinen 2005). The fullblown syndrome comprises a triad of: 1) billowing of the iris stroma in response to normal irrigation currents, 2) the floppy iris tends to prolapse through the phaco and the side port incisions, and 3) a progressive pupillary constriction during the surgical procedure. Althou...

OBJECTIVE The main objectives of this study were: To assess the incidence of the intraoperative floppy-iris syndrome associated with tamsulosin and to analyse the incidence of intraoperative and postoperative complications as compared to a control group. Secondary objectives were: to describe the pupillary modifications associated with tamsulosin and to quantify the endothelial cell loss. MET...

TNhe relation among the late systolic murmur, nonejection click, and prolapse of the mitral valve was established by Barlow and Pocock in 1963.1 In the past decade, 1,545 articles have discussed various aspects of this form of mitral regurgitation. How much this literature has added to our knowledge and to patient care is debatable. The pathology of the myxomatous mitral valve and related compl...

Since intraoperative floppy iris syndrome (IFIS) was first described in 2005, its association with the systemic alpha-1 adrenergic antagonist, tamsulosin (Flomax®, Boehringer-Ingelheim Pharmaceuticals, Inc., Ridgefield, CT), has become well established [1-7]. The clinical manifestations of IFIS complicating cataract surgery are poor preoperative pupil dilation, iris billowing and prolapse, and ...

BACKGROUND Mitral valve thickness is used as a criterion to distinguish the classical from the non-classical form of mitral valve prolapse (MVP). Classical form of MVP has been associated with higher risk of mitral regurgitation (MR) and concomitant complications. We sought to determine the relation of mitral valve morphology and motion to mitral regurgitation severity in patients with MVP. M...