Scope Around 25% of food allergic persons in Central Europe suffer from carrot allergy caused by the major allergen Dau c 1. Three different isoallergens, 1.01, 1.02 and 1.03 are identified. However, information about qualitative quantitative composition natural (n)Dau 1 is scarce. Methods Results The new 1.0401 identified on mRNA protein level RT-PCR mass spectrometry. It displays only around ...

Abstract Background Circular RNAs (circRNAs) have been reported to be important regulators of the development and progression various carcinomas. However, role circRNA_100290 in gastric cancer (GC) is still unclear. This study aimed investigate GC invasion metastasis possible underlying mechanism. Methods The expression cells tissues was examined using quantitative real-time polymerase chain re...

anti-adhesion therapy represents a potentially promising avenue for the treatment and prevention of tuberculosis in a post-antibiotic era. adhesins are surface-exposed microbial structures or molecules that enable pathogenic organisms to adhere to host surfaces, a fundamental step towards host infection. although several mycobacterium tuberculosis adhesins have been identified, it is predicted ...

fascioliasis is a worldwide parasitic disease in human and domestic animals. the causative agents of fascioliasis are fasciola hepatica and fasciola gigantica. in the recent years, fasciola resistance to drugs has been reported in the many of publications. fasciola spp has detoxification system including gst enzyme which may be responsible for its resistance. therefore , the aim of the study wa...

Abstract In Pseudomonas aeruginosa , Ttg2D is the soluble periplasmic phospholipid-binding component of an ABC transport system thought to be involved in maintaining asymmetry outer membrane. Here we use crystallographic structure at 2.5 Å resolution reveal that this protein can accommodate four acyl chains. Analysis available structures orthologs shows they conform a new substrate-binding-prot...

Abstract We describe results of testing blood donors in London, UK, for severe acute respiratory disease coronavirus 2 (SARS-CoV-2) IgG before and after lockdown measures. Anonymized samples from 17–69 years age were tested using 3 assays: Euroimmun IgG, Abbott an immunoglobulin receptor-binding domain assay developed by Public Health England. Seroprevalence increased 3.0% prelockdown (week 13,...