Simaba ferruginea (Simaroubaceae) is a Brazilian medicinal plant used in traditional medicine to treat several ailments, including gastric ulcers, fever, diarrhea, and dolorous and inflammatory processes. This study examines the chemical composition and antiulcerogenic effects of rhizomes from this plant. Bioassay-guided fractionation led to the isolation of two bioactive indole alkaloids calle...

Oxacyclic structures such as tetrahydrofuran (THF) rings are commonly found in many bioactive compounds, and this has led to several efforts toward their stereoselective syntheses. However, the process of catalytic asymmetric cycloetherification for their straightforward synthesis has remained a challenge. In this study, we demonstrate a novel asymmetric synthesis method for THF via the catalyt...

Phytochemical profile of the Central American rainforest endemic Annonaceae species, Annona pittieri and Cymbonopetallum costaricense, were studied in search novel bioactive compounds. The acetogenin squamocin (1) isolated from A. showed cytotoxic activity against human acute lymphocytic leukaemia with low healthy blood cells. In addition, other eight compounds pittieri, including a 2-azaanthra...

opium poppy (papaver somniferum l.) has two major products: alkaloids in the capsules and the seeds. it is known that opium poppy today contains alkaloid in great quantities. opiate alkaloids and their synthetic derivatives are widely used in medicines which are produced in hundreds of tons for the medicine industry. the study aimed to screen the capsules of six turkish opium poppy lines to eva...

The present study highlights the Bio activities and Pharmacology of Piper nigrum L. (Black Pepper). L is commonly known as Kali Mirch, Pippali, Milagu Peppercorn, White pepper, Green Black Madagascar pepper longum plant a deciduous slender aromatic climber. major source bioactive constituents in black fruits. It contains pungent alkaloid piperine (1-peperoyl piperidine) which to possess pharmac...

BACKGROUND The abortifacient claim of Senna alata (S. alata) was scientifically validated recently with alkaloids speculated to be the bioactive agent. This speculation is yet to be substantiated or refuted by scientific evidence. The present study was aimed to investigate the pregnancy terminating effects of the alkaloids from S. alata leaves. METHODS Twenty four Pregnant rats (143.99±1.21 g...