Bioheat transfer is the study of the transport of thermal energy in living systems. Because biochemical processes are temperature dependent, heat transfer plays a major role in living systems. Also, because the mass transport of blood through tissue causes a consequent thermal energy transfer, bioheat transfer methods are applicable for diagnostic and therapeutic applications involving either m...

In modern surgery, a multitude of minimally intrusive operational techniques are used which are based on the punctual heating of target zones of human tissue via laser or radio-frequency currents. Traditionally, these processes are modeled by the bioheat equation introduced by Pennes, who considers Fourier’s theory of heat conduction. We present an alternative and more realistic model establish...

The article is devoted to numerical methods for transient solution of Pennes’ bioheat equation as required for Magnetic Fluid Hyperthermia (MFH) modeling. Special attention has been paid to the role of non-linearity of blood perfusion and its influence on temperature distribution. The authors show that the higher-order time integration algorithms are highly advised for this type of problem, whi...

Based on the classical Pennes bioheat equation and oxygen diffusion equation, a new coupled heat-mass transfer model for characterizing the cerebral circulatory arrest is proposed. Two cooling approaches (the surface cooling and volumetric cooling) are applied to analyze the effect of hypothermia on the transient temperature and the oxygen consumption rate in different regions of brain. It is s...

This study demonstrates computer simulation of human brain treated with interstitial microwave hyperthermia. A thin coaxial-slot antenna emitting microwaves is the heat source. For simplification, a 2D axisymmetric model is considered. The wave equation for TM wave case and the Pennes bioheat transfer equation for transient-state have been solved with the finite element method. The impact of th...

The bioheat transfer simulation is undoubtedly the foundation for developing computerized tools for cryosurgery planning and analysis. While a large variety of techniques for bioheat transfer simulations are available in the literature of the past several decades, it is only their integration with clinical criteria and constraints which can make computerized planning a practical reality. This b...