نتایج جستجو برای: biomarker screening
تعداد نتایج: 282581 فیلتر نتایج به سال:
background: ovarian cancer is the most fatal tumor of female's reproductive system, and several genetics and environmental factors are involved in its development. various studies have already identified suitable biomarkers to facilitate the early detection, prognosis evaluation, and the assessment of treatment response. however, the aim of this review was to investigate the role of long n...
Epigenetic changes of DNA, including methylation, have long been recognized as key indicators various diseases, aging, cancer, and neurological disorders. Biomarker discoveries based on distinct methylation patterns for both hypermethylation hypomethylation lead the way in discovery novel diagnosis treatment targets. Many different approaches are present to detect level whole genome (whole bisu...
A fter decades of searching for a replacement for prostate-specific antigen (PSA) in prostate cancer screening, many researchers are once again examining variations on the long-beleaguered biomarker. PSA has withstood years of skepticism from critics who blame it for the overdiag-nosis and overtreatment of millions of men since it became the favorite prostate cancer screening test in the early ...
CONTEXT There is no rapid and cost effective tool that can be implemented as a front-line screening tool for Alzheimer's disease (AD) at the population level. OBJECTIVE To generate and cross-validate a blood-based screener for AD that yields acceptable accuracy across both serum and plasma. DESIGN, SETTING, PARTICIPANTS Analysis of serum biomarker proteins were conducted on 197 Alzheimer's ...
BACKGROUND The management of NSCLC has been transformed by stratified medicine. The National Lung Matrix Trial (NLMT) is a UK-wide study exploring the activity of rationally selected biomarker/targeted therapy combinations. PATIENTS AND METHODS The Cancer Research UK (CRUK) Stratified Medicine Programme 2 is undertaking the large volume national molecular pre-screening which integrates with t...
saliva is multifunctional; it is a lubricant for speech, aide for food digestion, and protective against microorganisms. it is voluntarily accessible, composed of proteins and electrolytes, and is ideal for the early detection of a wide range of diseases. because of a complex protein mixture, saliva proteomics has the potential to be a novel approach in the search for protein biomarkers. most s...
Purpose of review Niemann-Pick disease type C (NP-C) is a neurovisceral disorder that may be more prevalent than earlier estimates. Diagnosis of NP-C is often delayed; a key aim for clinical practice is to reduce this delay. Recently, substantial progress has been made in the field of NP-C screening and diagnosis, justifying an update to the existing recommendations for clinical practice. Rec...
Pancreatic cancer is the fourth most common cause of cancer-related mortality in the United States. Biomarkers are needed to detect this cancer early during the disease development and for screening populations to identify those who are at risk. In cancer, "biomarker" refers to a substance or process that is indicative of the presence of cancer in the body. A biomarker might be either a molecul...
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