Photoacoustic imaging also called optoacoustic or thermoacoustic imaging has the potential to image animal or human organs, such as the breast and the brain, with simultaneous high contrast and high spatial resolution. This article provides an overview of the rapidly expanding field of photoacoustic imaging for biomedical applications. Imaging techniques, including depth profiling in layered me...

Three-dimensional photoacoustic microscopy (PAM) has gained considerable attention within the biomedical imaging community during the past decade. Detecting laser-induced photoacoustic waves by optical sensing techniques facilitates the idea of all-optical PAM (AOPAM), which is of particular interest as it provides unique advantages for achieving high spatial resolution using miniaturized embod...

We report the development of an optical technique for noninvasive imaging of in vivo blood flow dynamics and tissue structures with high spatial resolution (2-10 microm) in biological systems. The technique is based on optical Doppler tomography (ODT), which combines Doppler velocimetry with optical coherence tomography to measure blood flow velocity at discrete spatial locations. The exception...

Optics and photonics are among the key technologies of 21st century offer potential for novel applications in areas as diverse sensing spectroscopy, analytics, monitoring, biomedical imaging diagnostics, well optical communication technology, others [...]

The field of medical imaging with polarized rare gases, just five years old, has brought optical scientists together with medical researchers to perfect techniques and pursue new opportunities for biomedical research. This review, written for the likely reader of these volumes, aims to present the field from several perspectives. The historical perspective shows how applications of nuclear pola...

J OINTLY assessing data from multiple modalities is inherent to many problems in science and engineering, but it is especially relevant to the analysis of biomedical imaging data. Technologies for imaging are individually expensive; thus, ways to synergistically derive information from complementary modalities are clearly attractive. Moreover, for instance, since each brain imaging modality is ...

Lanthanide-doped photon upconverting nanomaterials are emerging as a new class of imaging contrast agents, providing numerous unprecedented possibilities in the realm of biomedical imaging. Because of their ability to convert long-wavelength near-infrared excitation radiation into shorter-wavelength emissions, these nanomaterials are able to produce assets of low imaging background, large anti-...

Inverse methods form the basis of biomedical imaging applications, especially when they involve optical and near infrared radiation where multiple scattering tends to blur an image. This paper summarizes some of the recent literature on optical property reconstruction and on the use of fluorescence-induced signals for imaging. NOMENCLATURE cn Speed of light at refractive index n D Diffusion coe...