نتایج جستجو برای: bioreactors

تعداد نتایج: 3077  

Journal: :Biotechnology and Genetic Engineering Reviews 2008

Journal: :Chimia 2010
Sören Werner Regine Eibl Christine Lettenbauer Marcel Röll Dieter Eibl Maria De Jesus Xiaowei Zhang Matthieu Stettler Stephanie Tissot Cedric Bürki Gilles Broccard Markus Kühner Rolf Tanner Lucia Baldi David Hacker Florian M Wurm

Innovative mixing principles in bioreactors, for example using the rocking of a platform to induce a backwards and forwards 'wave', or using orbital shaking to generate a 'wave' that runs round in a cylindrical container, have proved to be successful for the suspension cultures of cells, especially when combined with disposable materials. This article presents an overview of the engineering cha...

Journal: :Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 2014
Soichi Yabuki

Long-term stability is a key property of enzyme membranes that can be used for biosensors, bioreactors, and bio-fuel cells. This review discusses factors that decrease the stability, and provides two examples of enzyme membranes, a polyion complex membrane and a cellulose membrane, with which stability loss can be avoided. By using these materials, long-term stability was improved. These suppor...

2002
Julio R. Banga Eva Balsa-Canto Carmen G. Moles Antonio A. Alonso

SUMMARY Model based optimization can be successfully used to improve the design and operation of bioreactors. In this contribution, we present a review of this area, especially focusing on the dynamic optimization of fed-batch bioreactors, a class of problems which has attracted (and continues to receive) huge attention. Both classical and more novel approaches, like those using bio-inspired op...

Journal: :Engineering in Life Sciences 2017

Journal: :Polish journal of microbiology 2007
Aleksandra Ziembińska Anna Raszka Jaak Truu Joanna Surmacz-Górska Korneliusz Miksch

Wastewater treatment based on activated sludge is known to be one of the most effective and popular wastewater purification methods. An estimation of microbial community variability in activated sludge allows us to observe the correlation between a particular bacterial group's appearance and the effectiveness of the removal of chemical substances. This research is focused on microbial community...

2004
B. Šantek

In this review, horizontal tubular bioreactors are discussed regarding their advantages and disadvantages compared to other bioreactor types. In horizontal tubular bioreactors medium flow is characterized by plug flow conditions that can be favorable in the case of inhibition and/or repression bioprocess kinetics. For description of liquid flow simple one-parameter or complex multi-parameters m...

2014
Henning Kempf Ruth Olmer Christina Kropp Michael Rückert Monica Jara-Avaca Diana Robles-Diaz Annika Franke David A. Elliott Daniel Wojciechowski Martin Fischer Angelica Roa Lara George Kensah Ina Gruh Axel Haverich Ulrich Martin Robert Zweigerdt

To harness the potential of human pluripotent stem cells (hPSCs), an abundant supply of their progenies is required. Here, hPSC expansion as matrix-independent aggregates in suspension culture was combined with cardiomyogenic differentiation using chemical Wnt pathway modulators. A multiwell screen was scaled up to stirred Erlenmeyer flasks and subsequently to tank bioreactors, applying control...

Journal: :Applied and environmental microbiology 1997
A Fang D L Pierson D W Koenig S K Mishra A L Demain

Production of the antibacterial polypeptide microcin B17 (MccB17) by Escherichia coli ZK650 was inhibited by simulated microgravity. The site of MccB17 accumulation was found to be different, depending on whether the organism was grown in shaking flasks or in rotating bioreactors designed to establish a simulated microgravity environment. In flasks, the accumulation was cellular, but in the rea...

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