Background: Carbapenem-resistant Acinetobacter baumannii strains are one of the most severe factors in hospital infection worldwide, which beta-lactamase enzyme is main resistance mechanisms. Objectives: This study aimed to evaluate presence carbapenem-resistant genes and determine antibiotic patterns clinical isolates A. from patients hospitalized Shahid Kamyab Hospital, Mashhad, Iran. Methods...

Background & Aims: The production of extended-spectrum-β-lactamases (ESBLs) is the main mechanism of resistance to β-lactam antibiotics. The outbreak of isolates simultaneously possessing several resistance mechanisms to β-lactam antibiotics caused a decrease in sensitivity of the confirmatory tests for ESBL. The aim of this study was the evaluation of the β-lactamase disk test method in the de...

Antimicrobial-resistant bacteria and resistance determinants are of great concern to human veterinary medicine worldwide. Extended-spectrum ?-lactamase (ESBL)-producing resistant broad-spectrum cephalosporins. ESBL-producing isolates, including those carrying blaCTX, blaPER, blaVEB, blaGES, have been reported from rivers in several countries.1 In a study performed 2018, using next-generation se...

PER-2 was the first detected and the second most prevalent extended-spectrum beta-lactamase in clinical pathogens isolated in Argentina and was also reported only in other South American countries. Citrobacter freundii 33587 was isolated in 1999 in Buenos Aires and was resistant to all tested beta-lactams except cephamycins and carbapenems. The strain produced both plasmid-borne TEM-1 and PER-2...

Abstract The purpose of this study was to define the prevalence gram negative bacteria that cause urinary tract infections (UTIs) and look for genes tetM, blaIMP, ND M-1 in uropathogenic Escherichia coli isolates. This conducted on 205 urine samples collected from outpatients having a infection Baquba teaching hospital. VITEK 2 compact device, which is fully automated, used identify causative m...

1. Paterson DL, Bonomo RA. Extended-spectrum b-lactamases: a clinical update. Clin Microbiol Rev 2005; 18: 657–86. 2. Naas T, Poirel L, Nordmann P. Minor extended-spectrum b-lactamases. Clin Microbiol Infect 2008; 14 Suppl 1: 42–52. 3. Poirel L, Cabanne L, Vahaboglü H et al. Genetic environment and expression of the extended-spectrum b-lactamase blaPER-1 gene in Gram-negative bacteria. Antimicr...

Due to annually recurring mass gatherings in Makkah, Saudi Arabia could be a hot spot for the collection of multidrug-resistant strains such as Pseudomonas aeruginosa (P. aeruginosa). The various genotypes of extended spectrum beta-lactamases (ESBLs) are SHV, TEM, CTX-M types VEB, PER, BEL-1, BES-1, ESBL enzymes in P. aeruginosa. The present study aimed to identify the prevalence these genes in...