Background: Effects of estrogen on bone metabolism and its protective role on prevention of osteoporosis are well   documented. However, the efficacy of estrogen treatment on bone healing is not well investigated. The drug can be delivered both systemically or locally to the bone with differences in concentrations and side effects. The aim of this study was to investigate the effect of lo...

Vertebral fractures are an under-recognized problem in children with glucocorticoid-induced osteoporosis (GIO). They cause severe back pain and spinal column deformity with a decrease of quality of life. For evaluating the bone mass, bone mineral density measurements have been widely carried out using dual energy X-ray absorptiometry. However, bone histomorphometric analyses of GIO in children ...

OBJECTIVES To compare bioactive glass and autograft regarding their histomorphometric characteristics. METHODS The authors conducted a prospective case-control experimental study on animals in order to compare the histomorphometric characteristics of bioactive glass versus autograft. Eight rabbits underwent surgery in which a cavitary defect was created in both proximal femurs. One side was f...

Several studies have established an association between diabetes and alterations in bone metabolism; however, the underlying mechanism is not well established. Although zinc is recognized as a potential preventive agent against diabetes-induced bone loss, there is no evidence demonstrating its effect in chronic diabetic conditions. This study evaluated the effects of zinc supplementation in a c...

objective: the aim of present study was to evaluate the quality, density and thickness of newly formed bone in experimental defects treated with combi-pack®, bio-oss® and biostite®. materials and methods: eight new zealand white rabbits were included in this randomized,blinded study. four equal 3×6 mm bone defects were created on the frontal and parietal bones of each animal and three were imme...

PURPOSE The purpose of this prospective study was to evaluate the effectiveness of newly developed autogenous tooth bone graft material (AutoBT)application for sinus bone graft procedure. MATERIALS AND METHODS The patients with less than 5.0 mm of residual bone height in maxillary posterior area were enrolled. For the sinus bone graft procedure, Bio-Oss was grafted in control group and AutoBT...

This study aimed to evaluate the histological, histomorphometric and radiographic features of the bone repair in ovariectomized rats submitted to mandibular distraction osteogenesis. Thirty female Wistar rats were equally divided in ovariectomy and control group and submitted to mandibular distraction osteogenesis. After 7, 14 and 28 days the animals were sacrificed and mandibles were removed a...

Statement of Problem: Reconstruction methods are an essential prerequisite for functional rehabilitation of the stomatognathic system. Platelet-rich plasma (PRP) offers a new and potentially useful adjunct to bone substitute materials (e.g. Xenografts) in oral and maxillofacial bone and implant reconstructive surgery. Purpose: An animal study was carried out to investigate the influence of PRP ...