نتایج جستجو برای: bone morphogenetic protein 2

تعداد نتایج: 3672045  

Journal: :The New England Journal of Medicine 2021

Pulmonary arterial hypertension is characterized by pulmonary vascular remodeling, cellular proliferation, and poor long-term outcomes. Dysfunctional bone morphogenetic protein pathway signaling associated with both hereditary idiopathic subtypes. Sotatercept, a novel fusion protein, binds activins growth differentiation factors in the attempt to restore balance between growth-promoting growth-...

Journal: :Journal of cellular biochemistry 2004
K D Brubaker E Corey L G Brown R L Vessella

Prostate cancer is the most commonly diagnosed malignancy in men and is often associated with bone metastases. Prostate cancer bone lesions can be lytic or schlerotic, with the latter predominating. Bone morphogenetic proteins (BMPs) are a family of growth factors, which may play a role in the formation of prostate cancer osteoblastic bone metastases. This study evaluated the effects of BMPs on...

Journal: :Brain : a journal of neurology 2010
Sridhar Reddy Chirasani Alexander Sternjak Peter Wend Stefan Momma Benito Campos Ilaria M Herrmann Daniel Graf Thimios Mitsiadis Christel Herold-Mende Daniel Besser Michael Synowitz Helmut Kettenmann Rainer Glass

Glioblastoma cells with stem-like properties control brain tumour growth and recurrence. Here, we show that endogenous neural precursor cells perform an anti-tumour response by specifically targeting stem-like brain tumour cells. In vitro, neural precursor cells predominantly express bone morphogenetic protein-7; bone morphogenetic protein-7 is constitutively released from neurospheres and indu...

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