Epithelioid sarcoma is a rare but aggressive soft tissue that presents significant diagnostic and management challenge to clinicians. We report 31-year-old female who presented with non-healing ulcer of three years’ duration on her left thumb after burn. Examination revealed an ulcerative tumour invading the bone areas haemorrhage. Microscopic examination showed epithelioid neoplasm central nec...

Kaposiform hemangioendothelioma (KHE) is a rare vascular neoplasm that can be potentially low malignant and mainly affects infants and adolescents. This tumor usually is seen in the skin, soft tissue, and retroperitoneum. This study is a case of KHE in the long bone of the ulna. The subject was a 7-year-old female patient with osteolytic lesion in the forearm without cutaneous lesions. Histolog...

The typical CT characteristics of glioblastoma multiforme (GBM) are well known . Glioblastomas usually enlarge by infiltrating adjacent brain parenchyma, without affecting the overlying bone. We report an unusual case of a temporal lobe GBM that destroyed the bone of the middle fossa and subsequently infiltrated the temporalis muscle. The presence of bone destruction on CT suggested an extraaxi...

Primary Lymphoma of Bone (PLB) is a very rare neoplasm presenting most commonly with bone pain and swelling or as an incidental finding on imaging. PLB diagnosis requires tissue biopsy and Non-Hodgkin’s lymphoma (NHL) is the commonest sub-type. Disease staging includes thoracic-abdominal-pelvic computed tomography scan (CT), bone marrow biopsy and cerebrospinal fluid cytology. Chemo-immunothera...

Myelofibrosis (MF) is a rare disorder that classified as one of the myeloproliferative disorders. It BCR-ABL1- negative neoplasm characterized by abnormal proliferation hemopoietic stem cells within bone marrow, which leads to overproduction fibrous tissue. Our patient young girl 17 year old presented with lump in left upper abdomen, shortness breath & generalized swelling. The diagnosis wa...

Introduction: Metastatic tumors of the temporal bone are extremely rare. Collet-Sicard syndrome is an uncommon condition characterized by unilateral palsy of the lower four cranial nerves. The clinical features of temporal bone metastasis are nonspecific and mimic infections such as chronic otitis media and mastoiditis.   Case Report: This report describes a rare case of metastatic adenocarcino...

Introducción: Germinal testicular tumors are the most common malignant neoplasm in men around 20 to 34 years. Even though they unusual, have increased incidence last decade; an excellent prognosis and overall survival at five years, approximately 95%. Divergent data exists regarding treatment options patients with first, second, third relapses conventional therapy. Some studies describe possibl...

background: understanding the differences in genetics of malignancies is crucial for therapeutic decisions. this systematic review was conducted to evaluate the current evidence on genetics of bone tumors in the context of pediatric cancer. material and methods: we performed a systematic review of the literature published on genetics of pediatrics bone tumors, using pubmed, google scholar, scie...

Abstract Plasmacytomas are localized monoclonal plasma cell lesions with no evidence of systemic involvement which divided into solitary bone plasmacytoma (SBP) and extra-medullary (EMP). The diagnosis plasmacytomas (PCM) in the oral regions is challenging given atypical clinical manifestations low frequency. Here, we report an extremely rare case elderly male initially appeared to be arising f...