echium amoenum fisch. and c.a. mey. (boraginaceae) is a very popular medicinal plant which is used as a tonic, tranquillizer, diaphoretic, cough remedy, sore throat and pneumonia in iran’s traditional medicine. callus culture of medicinal plants is one of the ways for production of secondary metabolites. in this study, callus culture of e. amoenum and its major secondary metabolite were investi...

BACKGROUND Research in the area of herbal psychopharmacology has clearly improved in recent decades. Self-administration of herbal medicines has been the most popular therapeutic alternative to standard medicine. OBJECTIVES Since the extract of Echium amoenum exhibits an anxiolytic effect, the aim of this study is to evaluate the anxiolytic and hypnotic effects in mice of the aqueous and etha...

Pontechium maculatum (Boraginaceae) is a species of high conservation concern in the Bulgarian flora. It assigned national IUCN category ‘Vulnerable’, legally protected according to Biological Diversity Act, and listed Annex II Habitats Directive (Council 92/43/EEC). Recent studies one largest populations country revealed some new data about which are reported here. The population studied situa...

In this work, microencapsulation of omega-3 lipids from sustainable sources, including oilseeds such as Salvia hispanica L., Echium plantagineum L. and Camelina sativa microalgal (from Nannochloropsis gaditana) enzymatically produced fatty acid ethyl esters (FAEEs), was successfully done by spray drying their outcomes studied. Previous to process, lipid extracts new sources (chia, camelina echi...

Echium amoenum Fisch. and C.A. Mey. (Boraginaceae) is a very popular medicinal plant which is used as a tonic, tranquillizer, diaphoretic, cough remedy, sore throat and pneumonia in Iran’s traditional medicine. Callus culture of medicinal plants is one of the ways for production of secondary metabolites. In this study, callus culture of E. amoenum and its major secondary metabolite were investi...

One adenoma and one adenocarcinoma of the islet cells and one adenoma of the exocrine pancreas were found in 3 out of 15 rats given a single dose (500 to 1500 mg/kg body weight) of pyrrolizidine alkaloids from Amsinckia intermedia Fisch and Mey (Boraginaceae), tarweed, a plant known to cause livestock losses from liver damage in the United States. Among rats treated with Heliotropium supinum L....

Pyrrolizidine alkaloids (PAs) in honey can be a potential human health risk. So far, it has remained unclear whether PAs in honey originate from pollen or floral nectar. We obtained honey, nectar, and plant pollen from two observation sites where Echium vulgare L. was naturally abundant. The PA concentration of honey was determined by targeted analysis using a high pressure liquid chromatograph...