PURPOSE To investigate beam quality correction, KQQ0 (r) and phantom scatter correction, Kphan (r) for lithium formate dosimeter as a function of distance r along the transverse axis of the high-energy brachytherapy sources 60Co, 137Cs, 192Ir and 169Yb using the Monte Carlo-based EGSnrc code system. MATERIALS AND METHODS The brachytherapy sources investigated in this study are BEBIG High Dose...

PURPOSE Well-known defect of TG-43 based algorithms used in brachytherapy is a lack of information about interaction cross-sections, which are determined not only by electron density but also by atomic number. TG-186 recommendations with using of MBDCA (model-based dose calculation algorithm), accurate tissues segmentation, and the structure's elemental composition continue to create difficulti...

In the recommendations of Task Group #43 from American Association of Physicists in Medicine (AAPM TG43), methods of brachytherapy source dosimetry are recommended, under full scattering conditions. However, in actual brachytherapy procedures, sources may not be surrounded by full scattering tissue in all directions. Clinical examples include high-dose-rate (HDR) brachytherapy of the breast or ...

BACKGROUND Recently, several randomized trials have demonstrated that intracoronary brachytherapy can reduce the rates of both angiographic and clinical restenosis in patients undergoing percutaneous coronary intervention (PCI) for in-stent restenosis. Whether this practice is cost-effective is unknown. METHODS AND RESULTS Between December 1997 and July 1998, 252 patients with in-stent resten...

The use of internal radiation from a gamma source in brachytherapy has been developing for several decades as a beneficial tool in the field of radiation therapy in medical physics. Brachytherapy has proved to be efficient for the treatment of tumors in a variety of organs that have different volumes and shapes. The use of brachytherapy treatment is based mainly on the AAPM protocol (TG-43) pub...

Introduction After the publication of Task Group number 43 dose calculation formalism by the American Association of Physicists in Medicine (AAPM), this method has been known as the most common dose calculation method in brachytherapy treatment planning. In this formalism, the water phantom is introduced as the reference dosimetry phantom, while the attenuation coefficient of the sources in the...

Introduction In this study, we aimed to calculate dose enhancement factor (DEF) for gold (Au) and iron (Fe) nanoparticles (NPs) in brachytherapy and teletherapy, using Monte Carlo (MC) method. Materials and Methods In this study, a new algorithm was introduced to calculate dose enhancement by AuNPs and FeNPs for Iridium-192 (Ir-192) brachytherapy and Cobalt-60 (Co-60) teletherapy sources, using...

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The Lecture covers the author's personal experience in brachytherapy in radiation oncology, beginning with low-dose rate (LDR) treatments using 226Ra "hot" sources, in the 1960s and early 1970s, through manual afterloading for treating gynaecological cancers with the same sources in the 1970s and 1980s, to high-dose rate (HDR) remote afterloading on a microSelectron HDR machine, from 1989 on. T...

In this study, we fabricated a Cerenkov fiber-optic dosimeter (CFOD) without any scintillator to measure Cerenkov radiation signals owing to gamma-rays. The relative depth dose (RDD) distributions of Ir-192 HDR brachytherapy source were obtained by using the CFOD based on a subtraction method and the RDD curve was compared with the simulation result of Monte Carlo N-particle extended transport ...