The BrainLes 2021 proceedings present research on glioma, multiple sclerosis, stroke and traumatic brain injuries.

Traumatic brain injury (TBI) is a major health concern worldwide. Laboratory studies utilizing animal models of TBI are essential for addressing pathological mechanisms of brain injury and development of innovative treatments. Over the past 75 years, pioneering head injury researchers have devised and tested a number of fluid percussive methods to reproduce the concussive clinical syndrome in a...

background traumatic brain injury (tbi) is an important public health problem throughout the world. objective this study assesses repeated glasgow coma scale (gcs) scores to predict the severity of tbi and survival of the patients. materials and methods a sample of 239 patients who were hospitalized with traumatic brain injury was selected by random sampling from icu wards at shahid beheshti ho...

OBJECTIVES Sport-related traumatic brain injuries are a significant public health burden, with hundreds of thousands sustained annually in North America. While sports offer numerous physical and social health benefits, traumatic brain injuries such as concussion can seriously impact a player's life, athletic career, and sport enjoyment. The culture in many sports encourages winning at all costs...

background: the role of renin angiotensin system (ras) in ischemic/reperfusion (i/r) injuries is not fully elucidated. furthermore, it is not clear whether inhibition of ras by angiotensin-converting enzyme (ace) inhibitors has beneficial effects in terms of protecting the brain from i/r injuries. in this study enalapril is used as an ace inhibitor to evaluate the role of ras in i/r injuries in...

An experimental study is conducted to investigate the rarefaction of untreated liquids in a spherical glass container due to a local. radial ultrasonic disturbance of sinusoidal. square pulse, or impulsive nature. Water and dilute polymer solution are used. The effects of the loading pattern and liquid properties on the location and magnitude of the maximum negative pressure in the fluid are ex...

Brain tissue modelling has been an active area of research for years. Brain matter does not follow the constitutive relations for common materials and loads applied to the brain turn into stresses and strains depending on tissue local morphology. In this work, a hyperviscoelastic fibre-reinforced anisotropic law is used for computational brain injury prediction. Thanks to a fibre-reinforcement ...

A surgical technique is described which enables chronic recording of electrophysiological activity and chemical or electrical stimulation in the decorticated animal. This procedure circumvents the problems of inadequate electrode/cannula patency and of the short-term debilitating consequences of cortical ablation. These features make it possible to analyze the relationships between neuroelectr...

The scientific literature suggests that barefoot activity may be beneficial. There is a current trend in recreational barefoot activity in children and adults, and barefoot running among athletes. Although the type of skin over most of the body (hairy skin) seems to be easily injured by painful abrading loads, little is known about protection provided by plantar sensory feedback against damage ...

ischemic stroke accounts for about 87 percent of all cases. it occurs as a result of an obstruction within a vessel of the brain and sudden loss of blood circulation to the corresponding area resulting in the loss of brain function. it is caused by thrombotic or embolic occlusion of an artery and is more common than hemorrhagic stroke. we know that most of the injuries after an acute ischemic s...